Honnurappa Vijayendra, Ramdass Sangeetha, Mahajan Nilesh, Vijayendra Vinay Kumar, Redleaf Miriam
1 Vijaya ENT Care Centre, Superspeciality Otology Centre, Bangalore, India.
2 Louis J. Mayer Professor of Otolaryngology, Director of Otology/Neurotology, Department of Otolaryngology, University of Illinois, Director of Ethiopian Otology Fellowship, Mekelle University, Chicago, Illinois, USA.
Ann Otol Rhinol Laryngol. 2019 Sep;128(9):848-854. doi: 10.1177/0003489419846143. Epub 2019 May 1.
Necrotizing otitis externa resolves best with antimicrobial treatment. How to care for these patients and monitor their resolution remains a problem. Our protocol in Bangalore can manage these patients inexpensively and well.
Patients who were referred to our patients became the subjects for this paper. They were managed through our protocol, which consists of IV ciprofloxacin and meropenem, weekly labs, weekly examinations, and photodocumention.
Fifty-one people presented with necrotizing otitis externa (NOE) between October 2015 and November 2017 and completed our entire protocol. Forty-six had complete resolution of their disease, while 5 had to undergo surgical removal of necrotic bone. Six of 8 patients with facial weakness had improvement in their House-Brackmann scores. Reduction of self-reported nocturnal pain, dissolution of ear canal granulations, and normalization of the erythrocyte sedimentation rate (ESR) proved to be the most accurate indicators of disease regression.
Patients are monitored closely with review of their otalgia, examination of their canal, repeated ESRs, effective control of their diabetes, and radiological imaging. All this can be done in a resource-poor country, which in turn serves as a model for the wealthier nations.
坏死性外耳道炎采用抗菌治疗效果最佳。如何护理这些患者并监测其病情好转情况仍是个问题。我们在班加罗尔的方案能够以低成本妥善管理这些患者。
转诊至我们这里的患者成为本文的研究对象。他们按照我们的方案进行管理,该方案包括静脉注射环丙沙星和美罗培南、每周进行实验室检查、每周进行体格检查以及拍照记录。
2015年10月至2017年11月期间,51例患者出现坏死性外耳道炎(NOE)并完成了我们的整个方案。46例患者疾病完全缓解,5例患者不得不接受坏死骨的手术切除。8例面部麻痹患者中有6例House-Brackmann评分有所改善。自我报告的夜间疼痛减轻、耳道肉芽组织消散以及红细胞沉降率(ESR)恢复正常被证明是疾病消退最准确的指标。
通过对耳痛的复查、耳道检查、重复检测ESR、有效控制糖尿病以及影像学检查对患者进行密切监测。所有这些在资源匮乏的国家都可以做到,这反过来也为较富裕国家提供了一个范例。