Institute of Mental Health, Government Mental Hospital, Amritsar, India.
Asia Pac Psychiatry. 2019 Dec;11(4):e12356. doi: 10.1111/appy.12356. Epub 2019 May 1.
The human population has been witnessing an increase in the number of diseases which are a consequence of progressively increasing physical and mental stress. Insomnia is one such condition whose prevalence is rising all over the world. Apart from the conventional behavioral interventions and use of benzodiazepines, the use of non-benzodiazepine drugs has seen a surge in recent times. The various adverse effects associated with benzodiazepines, dependence potential being one of them, led to an ever increasing use of non-benzodiazepine sedatives like zolpidem and zopiclone all over the world. But with their continuous and ever increasing use, it is seen that even these drugs carry dependence potential. Numerous cases of zolpidem abuse have been reported in literature until now. Here, we are presenting the case of a zolpidem-dependent patient who consumed it in quantities of 2400 mg/day, a quantity not reported anywhere in literature and around 240 times more than its usual prescribed daily dosage.
人类的疾病数量一直在增加，这些疾病是身体和精神压力不断增加的结果。失眠就是其中一种情况，其患病率在全球范围内呈上升趋势。除了传统的行为干预和使用苯二氮䓬类药物外，近年来非苯二氮䓬类药物的使用也有所增加。由于与苯二氮䓬类药物相关的各种不良反应，包括依赖潜力，导致全世界越来越多地使用非苯二氮䓬类镇静剂，如唑吡坦和佐匹克隆。但是，随着它们的持续和不断增加的使用，人们发现即使这些药物也具有潜在的依赖性。迄今为止，文献中已经报道了许多唑吡坦滥用的案例。在这里，我们报告了一例依赖唑吡坦的患者，他每天服用 2400 毫克，这一剂量在文献中没有报道过，是其通常规定的每日剂量的 240 倍以上。
