Department of Psychiatry, 117887Xiamen Xianyue Hospital, Xiamen, China.
Faculty of Health Sciences, Unit of Psychiatry, Department of Public Health and Medicinal Administration, and Institute of Translational Medicine, 59193University of Macau, Macao SAR, China.
J Geriatr Psychiatry Neurol. 2022 Mar;35(2):229-236. doi: 10.1177/08919887221078565.
The negative effect of the COVID-19 pandemic on sleep quality of clinically stable psychiatric patients is unknown. This study examined the prevalence of sleep disturbances and their association with quality of life (QOL) in clinically stable older psychiatric patients during the COVID-19 pandemic.
This multicenter, cross-sectional study involved older patients attending maintenance treatment at outpatient departments of four major psychiatric hospitals in China. Patients' socio-demographic and clinical characteristics were collected. Sleep disturbances, depressive symptoms, and QOL were assessed with the Insomnia Severity Index, the 9-item Patient Health Questionnaire, and 2 items of the World Health Organization Quality of Life-Brief version, respectively. Binary logistic regression analysis was conducted to examine the independent associations of socio-demographic and clinical variables with sleep disturbances, while the association between sleep disturbances and QOL was explored with analysis of covariance.
A total of 941 patients were recruited. The prevalence of sleep disturbances was 57.1% (95% CI: 53.9-60.2%). Analysis of covariance revealed that QOL was significantly lower in patients with sleep disturbances compared to those without. Multivariate logistic regression analysis showed that sleep disturbances were positively and independently associated with more severe depressive symptoms (OR = 1.32, 95% CI: 1.26-1.37). Compared to patients with major depressive disorder, those with other psychiatric diagnoses had a significantly higher prevalence of sleep disturbances (OR = 1.44, 95% CI: 1.00-2.08).
Sleep disturbances were common among clinically stable older psychiatric patients during the COVID-19 pandemic. Considering the negative association with QOL, this subpopulation needs regular assessment and timely treatment to reduce their sleep disturbances and improve their QOL.
COVID-19 大流行对临床稳定的精神科患者睡眠质量的负面影响尚不清楚。本研究旨在探讨 COVID-19 大流行期间，临床稳定的老年精神科患者睡眠障碍的发生率及其与生活质量（QOL）的关系。
这是一项多中心、横断面研究，纳入了中国四家主要精神病院门诊维持治疗的老年患者。收集患者的社会人口学和临床特征。使用失眠严重程度指数、9 项患者健康问卷和世界卫生组织生活质量简表的 2 项评估睡眠障碍、抑郁症状和 QOL。采用二元逻辑回归分析社会人口学和临床变量与睡眠障碍的独立关联，采用协方差分析探讨睡眠障碍与 QOL 的关系。
共纳入 941 例患者。睡眠障碍的患病率为 57.1%（95%CI：53.9-60.2%）。协方差分析显示，睡眠障碍患者的 QOL 明显低于无睡眠障碍患者。多变量逻辑回归分析显示，睡眠障碍与更严重的抑郁症状呈正相关且独立相关（OR=1.32，95%CI：1.26-1.37）。与抑郁症患者相比，其他精神科诊断患者睡眠障碍的患病率明显更高（OR=1.44，95%CI：1.00-2.08）。
COVID-19 大流行期间，临床稳定的老年精神科患者睡眠障碍较为常见。考虑到与 QOL 的负相关，该亚群需要定期评估和及时治疗，以减少其睡眠障碍，提高其 QOL。
