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Early use of abiraterone and radium-223 in metastatic prostate cancer.

作者信息

Cursano Maria Concetta, Santini Daniele, Iuliani Michele, Paganelli Giovanni, De Giorgi Ugo

机构信息

Department of Medical Oncology, Campus Bio-Medico University of Rome, 00128 Rome, Italy.

Department of Medical Oncology, Campus Bio-Medico University of Rome, 00128 Rome, Italy.

出版信息

Lancet Oncol. 2019 May;20(5):e228. doi: 10.1016/S1470-2045(19)30226-8.

DOI:10.1016/S1470-2045(19)30226-8
PMID:31044705
Abstract
摘要

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Early use of abiraterone and radium-223 in metastatic prostate cancer.阿比特龙和镭-223在转移性前列腺癌中的早期应用。
Lancet Oncol. 2019 May;20(5):e228. doi: 10.1016/S1470-2045(19)30226-8.
2
Early use of abiraterone and radium-223 in metastatic prostate cancer.阿比特龙和镭-223在转移性前列腺癌中的早期应用。
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Re: Addition of Radium-223 to Abiraterone Acetate and Prednisone or Prednisolone in Patients with Castration-resistant Prostate Cancer and Bone Metastases (ERA 223): A Randomised, Double-blind, Placebo-controlled, Phase 3 Trial.回复：在去势抵抗性前列腺癌和骨转移患者中，在醋酸阿比特龙和泼尼松或泼尼松龙基础上加用镭-223（ERA 223）：一项随机、双盲、安慰剂对照的3期试验。
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Combination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223?转移性去势抵抗性前列腺癌的联合治疗：我们能否通过添加镭-223 来安全提高疗效？
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Higher Risk of Fragility Fractures in Prostate Cancer Patients Treated with Combined Radium-223 and Abiraterone: Prednisone May Be the Culprit.镭-223 联合阿比特龙治疗的前列腺癌患者发生脆性骨折的风险更高：泼尼松可能是罪魁祸首。
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Combination therapies in prostate cancer: proceed with caution.前列腺癌的联合治疗：谨慎行事。
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Considering bone health in the treatment of prostate cancer bone metastasis based on the results of the ERA-223 trial.基于ERA - 223试验结果，在前列腺癌骨转移治疗中考虑骨骼健康。
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Efficacy and Safety of Abiraterone Acetate in Elderly (75 Years or Older) Chemotherapy Naïve Patients with Metastatic Castration Resistant Prostate Cancer.醋酸阿比特龙在老年（75岁及以上）初治转移性去势抵抗性前列腺癌患者中的疗效和安全性
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Abiraterone acetate for metastatic castration-resistant prostate cancer after docetaxel failure: A randomized, double-blind, placebo-controlled phase 3 bridging study.醋酸阿比特龙用于多西他赛治疗失败后的转移性去势抵抗性前列腺癌：一项随机、双盲、安慰剂对照的3期桥接研究。
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引用本文的文献

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Zoledronic Acid Prevents Bone Resorption Caused by the Combination of Radium-223, Abiraterone Acetate, and Prednisone in an Intratibial Prostate Cancer Mouse Model.唑来膦酸在胫骨内前列腺癌小鼠模型中可预防由镭-223、醋酸阿比特龙和泼尼松联合使用引起的骨吸收。
Cancers (Basel). 2023 Aug 15;15(16):4115. doi: 10.3390/cancers15164115.
2
Prognosis and safety of radium-223 with concurrent abiraterone acetate or enzalutamide use for metastatic castration-resistant prostate cancer: Real-world data of Japanese patients.镭-223联合醋酸阿比特龙或恩杂鲁胺治疗转移性去势抵抗性前列腺癌的预后与安全性：日本患者的真实世界数据
BJUI Compass. 2020 Sep 5;2(1):31-38. doi: 10.1002/bco2.42. eCollection 2021 Jan.
3
Fracture risk and survival outcomes in metastatic castration-resistant prostate cancer patients sequentially treated with abiraterone acetate and RADIUM-223.
接受醋酸阿比特龙和镭-223序贯治疗的转移性去势抵抗性前列腺癌患者的骨折风险和生存结果
Eur J Nucl Med Mol Imaging. 2020 Oct;47(11):2633-2638. doi: 10.1007/s00259-020-04796-w. Epub 2020 Apr 5.
4
Combination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223?转移性去势抵抗性前列腺癌的联合治疗：我们能否通过添加镭-223 来安全提高疗效？
Cancer Biol Ther. 2020;21(1):1-3. doi: 10.1080/15384047.2019.1665395. Epub 2019 Sep 18.