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Considering bone health in the treatment of prostate cancer bone metastasis based on the results of the ERA-223 trial.

作者信息

Mizokami Atsushi, Kimura Go, Fujii Yasuhisa, Hinotsu Shiro, Izumi Kouji

机构信息

Department of Urology, Kanazawa University, Kanazawa, Japan.

Department of Urology, Nippon Medical School, Tokyo, Japan.

出版信息

Int J Clin Oncol. 2019 Dec;24(12):1629-1631. doi: 10.1007/s10147-019-01518-7. Epub 2019 Sep 3.

DOI:10.1007/s10147-019-01518-7
PMID:31482239
Abstract
摘要

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Considering bone health in the treatment of prostate cancer bone metastasis based on the results of the ERA-223 trial.基于ERA - 223试验结果，在前列腺癌骨转移治疗中考虑骨骼健康。
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本文引用的文献

1
Addition of radium-223 to abiraterone acetate and prednisone or prednisolone in patients with castration-resistant prostate cancer and bone metastases (ERA 223): a randomised, double-blind, placebo-controlled, phase 3 trial.镭-223 联合醋酸阿比特龙和泼尼松或泼尼松龙治疗去势抵抗性前列腺癌和骨转移患者（ERA 223）：一项随机、双盲、安慰剂对照、III 期临床试验。
Lancet Oncol. 2019 Mar;20(3):408-419. doi: 10.1016/S1470-2045(18)30860-X. Epub 2019 Feb 6.
2
Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models.镭-223 通过双重靶向癌细胞和小鼠模型中的骨微环境抑制前列腺癌骨转移。
Clin Cancer Res. 2017 Aug 1;23(15):4335-4346. doi: 10.1158/1078-0432.CCR-16-2955. Epub 2017 Mar 31.
3
动态的骨转移变化预示着骨骼为主的状态，从而使接受镭-223 二氯化物治疗的去势抵抗性前列腺癌患者受益。
Cancer Med. 2020 Nov;9(22):8579-8588. doi: 10.1002/cam4.3459. Epub 2020 Sep 22.
A Randomised Comparison Evaluating Changes in Bone Mineral Density in Advanced Prostate Cancer: Luteinising Hormone-releasing Hormone Agonists Versus Transdermal Oestradiol.一项评估晚期前列腺癌骨矿物质密度变化的随机对照研究：促黄体生成素释放激素激动剂与经皮雌二醇的比较
Eur Urol. 2016 Jun;69(6):1016-25. doi: 10.1016/j.eururo.2015.11.030. Epub 2015 Dec 17.
4
Oral ethinylestradiol in castration-resistant prostate cancer: a 10-year experience.口服炔雌醇治疗去势抵抗性前列腺癌：十年经验
Int J Urol. 2015 Jan;22(1):98-103. doi: 10.1111/iju.12613. Epub 2014 Sep 3.
5
Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: exploratory analysis of data from the COU-AA-301 randomised trial.醋酸阿比特龙与泼尼松对比安慰剂与泼尼松在转移性去势抵抗性前列腺癌患者中对疼痛控制和骨骼相关事件的影响：来自 COU-AA-301 随机试验数据的探索性分析。
Lancet Oncol. 2012 Dec;13(12):1210-7. doi: 10.1016/S1470-2045(12)70473-4. Epub 2012 Nov 9.
6
Ethinylestradiol improves prostate-specific antigen levels in pretreated castration-resistant prostate cancer patients.炔雌醇可改善预处理去势抵抗性前列腺癌患者的前列腺特异性抗原水平。
Anticancer Res. 2010 Dec;30(12):5201-5.
7
Low free testosterone predicts frailty in older men: the health in men study.游离睾酮水平低预示老年男性衰弱：男性健康研究。
J Clin Endocrinol Metab. 2010 Jul;95(7):3165-72. doi: 10.1210/jc.2009-2754. Epub 2010 Apr 21.
8
Estrogens as regulators of bone health in men.雌激素作为男性骨骼健康的调节因子。
Nat Rev Endocrinol. 2009 Aug;5(8):437-43. doi: 10.1038/nrendo.2009.112. Epub 2009 Jun 16.