Yang Yingchao, Ma Yeshuo, Yin Da, Zhang Ying, Song Wei, Cheng Yunpeng, Fu Tingting, Zhang Ri, Liu Yue, Kang Kai, Wang Lixin, Jiang Yinong, Lu Yan
Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University.
Department of Cardiology, The Third Xiangya Hospital of Central South University, Changsha, Hunan.
Medicine (Baltimore). 2019 May;98(18):e15436. doi: 10.1097/MD.0000000000015436.
de Winter electrocardiograph (ECG) pattern signifies proximal left anterior descending coronary artery (LAD) occlusion and extensive anterior myocardial infarction, and it is found in about 2% of patients with proximal LAD occlusion. However, it is often unrecognized by physicians. In this case report, we present a patient with chest pain but showing an atypical and delayed de Winter ECG pattern.
A previously healthy 61-year-old man attended our emergency department with chest pain radiating to the left arm and back for 4 hours, who was without serious cardiovascular risk factors. ECG at emergency department showed no significant changes. High-sensitivity cardiac troponin I (hs-cTnI) was within normal limit.
At 5 hours after onset, ECG showed significant upsloping ST depression at J point in precordial leads V3 to V6, slight ST elevation in aVR and depression in inferior leads, and hs-cTnI peaked at 2.610 μg/L. The diagnosis of de Winter ECG pattern was confirmed by coronary angiography with an occlusion of the proximal LAD.
A stent was implanted through percutaneous coronary intervention.
The patient's chest pain was relieved without further increase of hs-cTnI. ECG after procedure showed ST segment back to baseline in leads V4 to V6, but persistent ST elevation in V1 to V3 with QS or Q wave.
Timely diagnosis of de Winter ECG pattern is very important, especially the atypical and delayed ECG changes. It should be treated as ST elevation myocardial infarction equivalent and deserves emergent revascularization therapy.
de Winter心电图模式提示左前降支近端冠状动脉(LAD)闭塞及广泛前壁心肌梗死,约2%的LAD近端闭塞患者会出现这种情况。然而,医生常常未能识别。在本病例报告中,我们呈现了一名胸痛患者,但其表现出非典型且延迟出现的de Winter心电图模式。
一名61岁既往健康男性因胸痛放射至左臂及背部4小时就诊于我院急诊科,其无严重心血管危险因素。急诊科心电图无显著变化。高敏心肌肌钙蛋白I(hs-cTnI)在正常范围内。
发病5小时后,心电图显示胸前导联V3至V6的J点处ST段显著上斜型压低,aVR导联轻度ST段抬高及下壁导联ST段压低,hs-cTnI峰值为2.610μg/L。冠状动脉造影证实LAD近端闭塞,确诊为de Winter心电图模式。
通过经皮冠状动脉介入植入支架。
患者胸痛缓解,hs-cTnI未进一步升高。术后心电图显示V4至V6导联ST段恢复至基线,但V1至V3导联ST段持续抬高伴QS或Q波。
及时诊断de Winter心电图模式非常重要,尤其是非典型及延迟的心电图改变。应将其视为等同于ST段抬高型心肌梗死,值得紧急进行血运重建治疗。