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桥本甲状腺炎伴自发性颅内低压:一例报告。

Spontaneous intracranial hypotension in Hashimoto's thyroiditis: A case report.

作者信息

Liang Hui, Xu Congjie, Liu Tao, Huang Shixiong, Hu Shijun

机构信息

Department of Neurology.

Department of Urology, Hainan General Hospital, Haikou, P. R. China.

出版信息

Medicine (Baltimore). 2019 May;98(18):e15476. doi: 10.1097/MD.0000000000015476.

Abstract

RATIONALE

Autoimmune thyroid diseases (ATDs) seldom affect intracranial pressure. Here, we describe a case of spontaneous intracranial hypotension (SIH) related to Hashimoto's thyroiditis (HT), which has never been previously published.

PATIENT CONCERNS

A 54-year-old woman was admitted to our hospital due to sudden-onset postural headache, neck pain stiffness, visual blurring, nausea and vomiting. The headache was aggravated when the patient sat or stood up yet rapidly resolved within 1 minute after recumbency.

DIAGNOSIS

The patient had a grade 1a diffusely palpable thyroid gland and the laboratory report revealed elevated titers of anti-thyroid antibodies, a diagnosis of HT was established. Gadolinium-enhanced magnetic resonance imaging exhibited dilatation of the venous sinuses, obvious diffuse pachymeningeal enhancement, and narrowing of the ventricular system, combined with the lumbar puncture pressure was 60 mmH20 in the lateral recumbent position, and a diagnosis of SIH was eatablished.

INTERVENTIONS

The patient was placed on strict bed rest and hydrated for 15 days.

OUTCOMES

The headache was gradually relieved, a follow-up at 1 month after discharge revealed that the patient could stand and function normally.

LESSONS

SIH can be related to ATD.

摘要

理论依据

自身免疫性甲状腺疾病(ATD)很少影响颅内压。在此,我们描述一例与桥本甲状腺炎(HT)相关的自发性颅内低压(SIH)病例,此前从未有过相关报道。

患者情况

一名54岁女性因突发体位性头痛、颈部疼痛僵硬、视力模糊、恶心和呕吐入院。患者坐起或站立时头痛加重,但卧位后1分钟内迅速缓解。

诊断

患者甲状腺1a级弥漫性可触及,实验室报告显示抗甲状腺抗体滴度升高,确诊为HT。钆增强磁共振成像显示静脉窦扩张、明显的弥漫性硬脑膜强化以及脑室系统变窄,同时侧卧位腰椎穿刺压力为60 mmH20,确诊为SIH。

干预措施

患者严格卧床休息并补液15天。

结果

头痛逐渐缓解,出院后1个月随访显示患者能够正常站立和活动。

经验教训

SIH可能与ATD有关。

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