Walker Kendra, Martini Angela, Philips Haley, Sharp Leigha, Thomas Kleesy, Tarbox Michelle
Texas Tech University Health Sciences Center School of Medicine, Lubbock, Texas.
Dermatol Online J. 2019 Apr 15;25(4):13030/qt4qg8s971.
Darier disease (DD), also known as keratosis follicularis or Darier-White disease, is a rare autosomal dominant genodermatosis that presents as hyperkeratotic, warty papules affecting the seborrheic and intertriginous areas. Patients with DD are at risk of secondary infections including the rare complication of Kaposi varicelliform eruption (KVE), a widespread viral infection most commonly caused by herpes simplex virus (HSV). Darier disease with secondary KVE can lead to widespread systemic infection and death. This case report discusses an individual with DD who subsequently developed KVE due to disseminated HSV type 2 infection.
达里埃病（DD），也称为毛囊角化病或达里埃-怀特病，是一种罕见的常染色体显性遗传性皮肤病，表现为影响脂溢性和褶皱部位的角化过度、疣状丘疹。DD患者有继发感染的风险，包括罕见的卡波西水痘样疹（KVE）并发症，这是一种最常见由单纯疱疹病毒（HSV）引起的广泛病毒感染。伴有继发性KVE的达里埃病可导致广泛的全身感染和死亡。本病例报告讨论了一名患有DD的个体，其随后因播散性2型HSV感染而发生KVE。
