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Chronic Stress Causes Projection-Specific Adaptation of Amygdala Neurons via Small-Conductance Calcium-Activated Potassium Channel Downregulation.慢性应激通过小电导钙激活钾通道下调导致杏仁核神经元的投射特异性适应。
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Physiological role of calcium-activated potassium currents in the rat lateral amygdala.钙激活钾电流在大鼠杏仁核外侧的生理作用。
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Fear conditioning suppresses large-conductance calcium-activated potassium channels in lateral amygdala neurons.恐惧条件作用抑制杏仁核外侧神经元中的大电导钙激活钾通道。
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Distribution of the messenger RNA for the small conductance calcium-activated potassium channel SK3 in the adult rat brain and correlation with immunoreactivity.
Neuroscience. 2001;102(1):209-15. doi: 10.1016/s0306-4522(00)00486-3.
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Small conductance calcium activated potassium (SK) channel dependent and independent effects of riluzole on neuropathic pain-related amygdala activity and behaviors in rats.利鲁唑对大鼠神经病理性疼痛相关杏仁核活动和行为的小电导钙激活钾 (SK) 通道依赖性和非依赖性影响。
Neuropharmacology. 2018 Aug;138:219-231. doi: 10.1016/j.neuropharm.2018.06.015. Epub 2018 Jun 13.
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SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala.小电导钙激活钾通道调节杏仁核外侧的兴奋性突触传递和可塑性。
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Similar nicotinic excitability responses across the developing hippocampal formation are regulated by small-conductance calcium-activated potassium channels.发育中的海马结构中相似的烟碱能兴奋性反应受小电导钙激活钾通道调控。
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Rat GnRH neurons exhibit large conductance voltage- and Ca2+-Activated K+ (BK) currents and express BK channel mRNAs.大鼠促性腺激素释放激素（GnRH）神经元表现出大电导电压和钙离子激活的钾离子（BK）电流，并表达BK通道信使核糖核酸（mRNAs）。
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Impact of calcium-activated potassium channels on NMDA spikes in cortical layer 5 pyramidal neurons.钙激活钾通道对皮层第5层锥体神经元中N-甲基-D-天冬氨酸（NMDA）尖峰的影响。
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A comprehensive analysis of allele-specific expression and transcriptomic profiling in pig limbic and endocrine tissues.猪边缘系统和内分泌组织中基因特异性表达与转录组分析的综合研究
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Microbial metabolites tune amygdala neuronal hyperexcitability and anxiety-linked behaviors.微生物代谢产物调节杏仁核神经元的过度兴奋性和焦虑相关行为。
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本文引用的文献
1
Chronic Stress Causes Projection-Specific Adaptation of Amygdala Neurons via Small-Conductance Calcium-Activated Potassium Channel Downregulation.慢性应激通过小电导钙激活钾通道下调导致杏仁核神经元的投射特异性适应。
Biol Psychiatry. 2019 May 15;85(10):812-828. doi: 10.1016/j.biopsych.2018.12.010. Epub 2018 Dec 20.
2
Chronic Stress Remodels Synapses in an Amygdala Circuit-Specific Manner.慢性应激以杏仁核环路特异的方式重塑突触。
Biol Psychiatry. 2019 Feb 1;85(3):189-201. doi: 10.1016/j.biopsych.2018.06.019. Epub 2018 Jul 5.
3
Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man.创伤后应激障碍中的大脑回路功能障碍：从老鼠到人。
Nat Rev Neurosci. 2018 Sep;19(9):535-551. doi: 10.1038/s41583-018-0039-7.
4
Organization of Valence-Encoding and Projection-Defined Neurons in the Basolateral Amygdala.外侧杏仁核中价态编码和投射定义神经元的组织。
Cell Rep. 2018 Jan 23;22(4):905-918. doi: 10.1016/j.celrep.2017.12.097. Epub 2018 Jan 28.
5
Resolving the neural circuits of anxiety.解析焦虑的神经回路。
Nat Neurosci. 2015 Oct;18(10):1394-404. doi: 10.1038/nn.4101. Epub 2015 Sep 25.
6
Targeting the Small- and Intermediate-Conductance Ca-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface.靶向小电导和中电导钙激活钾通道：通道/钙调蛋白界面处的药物结合口袋。
Neurosignals. 2014;22(2):65-78. doi: 10.1159/000367896. Epub 2014 Oct 8.
7
SK2 potassium channel overexpression in basolateral amygdala reduces anxiety, stress-induced corticosterone secretion and dendritic arborization.基底外侧杏仁核中SK2钾通道的过表达可减轻焦虑、应激诱导的皮质酮分泌及树突分支。
Mol Psychiatry. 2009 Sep;14(9):847-55, 827. doi: 10.1038/mp.2009.9. Epub 2009 Feb 10.
8
Treatment-resistant anxiety disorders.难治性焦虑症
Mol Psychiatry. 2006 Sep;11(9):805-14. doi: 10.1038/sj.mp.4001852. Epub 2006 Jul 18.
9
SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala.小电导钙激活钾通道调节杏仁核外侧的兴奋性突触传递和可塑性。
Nat Neurosci. 2005 May;8(5):635-41. doi: 10.1038/nn1450. Epub 2005 Apr 24.
10
Small conductance Ca2+-activated K+ channels modulate synaptic plasticity and memory encoding.小电导钙激活钾通道调节突触可塑性和记忆编码。
J Neurosci. 2002 Dec 1;22(23):10163-71. doi: 10.1523/JNEUROSCI.22-23-10163.2002.
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