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有效利用实验室检查对炎症性肠病患者的管理。

Effective Use of the Laboratory in the Management of Patients with Inflammatory Bowel Diseases.

机构信息

Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Iowa, Carver College of Medicine, University of Iowa Hospitals and Clinics, 4546 JCP, 200 Hawkins Drive, Iowa City, IA 52242, USA.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Iowa, Carver College of Medicine, University of Iowa Hospitals and Clinics, 4607 JCP, 200 Hawkins Drive, Iowa City, IA 52242, USA.

出版信息

Gastroenterol Clin North Am. 2019 Jun;48(2):237-258. doi: 10.1016/j.gtc.2019.02.006.

DOI:10.1016/j.gtc.2019.02.006
PMID:31046973
Abstract

Inflammatory bowel disease (IBD) comprises a group of chronic, intestinal inflammatory disorders, including ulcerative colitis and Crohn's disease. IBD is characterized by periods of relapse and remission. Long-term progressive intestinal inflammation can result in severe and devastating complications, such as intestinal strictures and/or fistulae. Immune suppressive medications with potent side effects are often used to control inflammation and limit disease activity. Laboratory tests guide various decisions in clinical management of IBD. We discuss tests used to diagnose IBD, assess for relapse or remission, monitor the effectiveness of therapeutic regimen, screen for the maintenance of health, and diagnose or prevent complications.

摘要

炎症性肠病(IBD)包括一组慢性肠道炎症性疾病,包括溃疡性结肠炎和克罗恩病。IBD 的特点是反复发作和缓解。长期进行性肠道炎症可导致严重和破坏性的并发症,如肠道狭窄和/或瘘管。常使用具有严重副作用的免疫抑制药物来控制炎症和限制疾病活动。实验室检查指导 IBD 的临床管理中的各种决策。我们讨论用于诊断 IBD、评估复发或缓解、监测治疗方案的有效性、筛查健康维持、诊断或预防并发症的检查。

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