Jain Rajendra Singh, Kumar Sunil, Tejwani Shankar
Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, India.
Department of Neurology, Sawai Man Singh Medical College, Jaipur, Rajasthan, India.
J Med Imaging Radiat Sci. 2016 Mar;47(1):113-115. doi: 10.1016/j.jmir.2015.10.001. Epub 2015 Dec 2.
Multiple-system atrophy (MSA) is a progressive neurodegenerative disorder. It is characterized by dysfunction of multiple systems including autonomic, extrapyramidal, pyramidal and cerebellar. Pontine hot-cross bun (HCB) sign in MSA is a well-documented and highly specific entity. To the best of our knowledge, medullary hot-cross bun (HCB) sign has never been described in literature. Herein, we report a case of MSA-C with medullary HCB sign. Detection of medullary HCB sign might be a surrogate marker in the diagnosis of MSA-C, particularly in the absence of classical pontine HCB sign; however, further research will help to validate this sign.
多系统萎缩（MSA）是一种进行性神经退行性疾病。它的特征是多个系统功能障碍，包括自主神经系统、锥体外系、锥体系统和小脑。MSA中的脑桥“热十字面包”（HCB）征是一个有充分文献记载且高度特异的表现。据我们所知，延髓“热十字面包”（HCB）征在文献中从未被描述过。在此，我们报告一例伴有延髓HCB征的MSA-C病例。延髓HCB征的检测可能是MSA-C诊断中的一个替代标志物，特别是在没有经典脑桥HCB征的情况下；然而，进一步的研究将有助于验证这一征象。
