Hoang Van-Thuan, Goumballa Ndiaw, Dao Thi-Loi, Ly Tran Duc Anh, Ninove Laetitia, Ranque Stéphane, Raoult Didier, Parola Philippe, Sokhna Cheikh, Pommier de Santi Vincent, Gautret Philippe
Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, IHU-Méditerranée Infection, Marseille, France; Thai Binh University of Medicine and Pharmacy, Viet Nam.
VITROME, Campus International IRD/UCAD de Hann, Dakar, Senegal.
Travel Med Infect Dis. 2019 Nov-Dec;32:101410. doi: 10.1016/j.tmaid.2019.04.010. Epub 2019 May 3.
The Grand Magal of Touba is the largest Muslim pilgrimage in Senegal with a potential for infectious disease transmission.
Clinical follow-up, adherence to preventive measures and qPCR-based respiratory and gastrointestinal pathogens carriage pre- and post-Magal, were assessed.
110 pilgrims from South Senegal were included. The duration of stay in Touba was 3 days. 41.8% and 14.5% pilgrims reported respiratory and gastrointestinal symptoms. Most individuals having the onset of symptoms during their stay in Touba, or soon after returning. The acquisition of rhinoviruses, coronaviruses and adenovirus was 13.0, 16.7 and 4.6% respectively and that of Streptococcus pneumoniae and Haemophilus influenzae was 3.7% and 26.9%. Acquisition of gastrointestinal viruses and parasites was low, while bacterial acquisition ranged from 2.2% for Campylobacter jejuni to 33.0% for enteropathogenic Escherichia coli.
This preliminary study confirms that Grand Magal pilgrims are likely to be exposed to communicable disease risk as observed in other pilgrimage settings. Further study including larger numbers of pilgrims are needed to investigate potential risk factors for respiratory and gastrointestinal infections at the Grand Magal.
图巴大朝觐是塞内加尔最大的穆斯林朝圣活动，存在传染病传播的可能性。
对临床随访、预防措施的依从性以及基于定量聚合酶链反应的朝觐前后呼吸道和胃肠道病原体携带情况进行了评估。
纳入了110名来自塞内加尔南部的朝圣者。在图巴的停留时间为3天。41.8%和14.5%的朝圣者报告有呼吸道和胃肠道症状。大多数人在图巴停留期间或返回后不久出现症状。鼻病毒、冠状病毒和腺病毒的感染率分别为13.0%、16.7%和4.6%，肺炎链球菌和流感嗜血杆菌的感染率分别为3.7%和26.9%。胃肠道病毒和寄生虫的感染率较低，而细菌感染率从空肠弯曲菌的2.2%到致病性大肠杆菌的33.0%不等。
这项初步研究证实，正如在其他朝圣活动中所观察到的那样，图巴大朝觐的朝圣者可能面临传染病风险。需要进行包括更多朝圣者的进一步研究，以调查图巴大朝觐期间呼吸道和胃肠道感染的潜在风险因素。
