Department of Biomaterials Science and Turku Clinical Biomaterials Center - TCBC, Institute of Dentistry, University of Turku, Itäinen Pitkäkatu 4B, FI-20520, Turku, Finland; Biomaterial and Medical Device Research Programme - BioCity Turku, Itäinen Pitkäkatu 4B, FI-20520, Turku, Finland.
Department of Biomaterials Science and Turku Clinical Biomaterials Center - TCBC, Institute of Dentistry, University of Turku, Itäinen Pitkäkatu 4B, FI-20520, Turku, Finland; Biomaterial and Medical Device Research Programme - BioCity Turku, Itäinen Pitkäkatu 4B, FI-20520, Turku, Finland.
J Mech Behav Biomed Mater. 2019 Aug;96:172-185. doi: 10.1016/j.jmbbm.2019.04.016. Epub 2019 Apr 17.
In toy-breed dogs (bodyweight <5 kg), the fractures of the radius and ulna are particularly common and can be caused by minimal trauma. While fracture fixation using metallic plates is a feasible treatment modality, the excessive stiffness of these devices produces the underloading of the bone which may result in the adverse bone remodelling and complications in the healing of the fracture. In this study, we investigated bisphenol A glycidylmethacrylate -based glass fibre reinforced composites as potential alternatives to metals in the devices intended for the fracture fixation of the distal radius in toy-breed dogs. Four composites with different glass fibre reinforcements were prepared as rectangular specimens and as fracture fixation plates. These were mechanically tested in three-point and four-point bending. There were two controls: polyether etherketone reinforced with short carbon fibres (specimens and plates) and commercially available stainless-steel plates. Finite element simulations were used for the assessment of the behaviour of the plates. For the control stainless steel plate, the bending strength was 1.358 Nm, superior to that of any of the composite plates. The composite plate with the matrix reinforced with continuous unidirectional glass fibres had the bending strength of 1.081 Nm, which is sufficient in this clinical context. For the plates made of polyether etherketone reinforced with carbon fibres, the strength was 0.280 N*m. Similar conclusions on the biomechanical behaviour of the plates could be made solely based on the results of the finite element simulations, provided the geometries and the material properties are well defined.
在玩具犬种（体重<5kg）中，桡骨和尺骨骨折尤为常见，可能由轻微创伤引起。虽然使用金属板进行骨折固定是一种可行的治疗方式，但这些设备的过高刚性会导致骨骼承受的负荷不足，从而可能导致不良的骨骼重塑和骨折愈合并发症。在这项研究中，我们研究了双酚 A 甲基丙烯酸缩水甘油酯基玻璃纤维增强复合材料作为用于玩具犬种桡骨远端骨折固定装置中替代金属的潜在材料。制备了四种不同玻璃纤维增强的复合材料作为矩形试件和骨折固定板。对这些试件和板进行了三点和四点弯曲力学测试。有两个对照组：用短碳纤维增强的聚醚醚酮（试件和板）和市售的不锈钢板。使用有限元模拟评估了板的行为。对于对照不锈钢板，弯曲强度为 1.358Nm，优于任何一种复合板。用连续单向玻璃纤维增强基体的复合板的弯曲强度为 1.081Nm，在这种临床情况下足够了。对于用碳纤维增强的聚醚醚酮板，强度为 0.280N*m。如果能够很好地定义几何形状和材料特性，则仅基于有限元模拟的结果就可以得出关于板的生物力学行为的类似结论。
