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使用脱细胞真皮基质进行口腔重建以矫正小口畸形

Correction of Microstomia Reconstruction With the Use of Acellular Dermal Matrix for Buccal Reconstruction.

作者信息

Wood Benjamin C, Mantilla-Rivas Esperanza, Goldrich Agnes, Boyajian Michael K, Oh Albert K, Rogers Gary F, Boyajian Michael J

机构信息

Division of Plastic Surgery, Children's National Health System, Washington, DC.

College of Agriculture and Life Sciences, Cornell University, Ithaca, NY.

出版信息

J Craniofac Surg. 2019 May/Jun;30(3):736-738. doi: 10.1097/SCS.0000000000005182.

Abstract

Correction of microstomia is challenging with a high rate of recurrence. We report the successful treatment of microstomia using acellular dermal matrix (ADM) as an adjunct for intraoral lining with >1 year of follow-up.A 9-year-old international patient with severe immunodeficiency presented with severe microstomia because of recurrent oral infections. She had undergone 3 previous failed attempts to re-establish an adequate oral opening and was dependent on enteral nutrition via gastrostomy tube. She underwent release of the oral commissure scar contracture and orbicularis oris and the resultant mucosal defect was lined with ADM. A postoperative splint was used for 8 weeks. One-year follow-up demonstrated maintenance of the oral aperture with complete mucosalization of the ADM; the patient was able to resume oral diet and regular dental hygiene.Mucosal reconstruction with ADM is a viable alternative to local flaps and in this case exhibited minimal soft tissue contraction.

摘要

小口症的矫正具有挑战性,复发率很高。我们报告了使用脱细胞真皮基质(ADM)作为口腔内衬辅助材料成功治疗小口症的案例,并进行了超过1年的随访。一名9岁的患有严重免疫缺陷的国际患者因反复口腔感染出现严重小口症。她之前曾3次尝试重建足够的口腔开口但均失败,依靠胃造瘘管进行肠内营养。她接受了口角瘢痕挛缩松解术以及口轮匝肌松解术,随后用ADM修复了由此产生的黏膜缺损。术后使用夹板8周。1年的随访显示口腔开口得以维持,ADM完全黏膜化;患者能够恢复经口饮食并保持正常的口腔卫生。用ADM进行黏膜重建是局部皮瓣的一种可行替代方法,在本案例中显示软组织收缩极小。

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