Theos Kimberly R, Johnson Kory M, Johnson Douglas W
John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI.
Hawaii J Med Public Health. 2019 May;78(5):163-168.
is a pathogen that causes skin and soft tissue infections (SSTIs) in dermatology patients. There is an increasing rate of methicillin-resistant (MRSA) reported in the dermatology literature since 1987. This report profiles the antibiotic susceptibilities of methicillin-sensitive (MSSA) and MRSA in an outpatient office in Hawai'i. This is a retrospective study done by chart review from 2012 to 2014. Demographics, anatomical site of infection, clinical diagnoses and antimicrobial susceptibility patterns were analyzed and compared. Of the 66 samples, 57% were males and 43% were females. was more commonly found in impetigo, folliculitis, furuncles and secondarily infected psoriasis and more commonly located on the extremities. MSSA accounted for 73% (48) of the cases and MRSA accounted for 27% (18) of the cases. The antibiotics most effective against all cultures for outpatients were linezolid (100%), trimethoprim sulfamethoxazole (95%) and tetracyclines (94%). Linezolid (100%), trimethoprim sulfamethoxazole (100%) were most effective against MRSA isolates. Our and MRSA antimicrobial susceptibility results are similar to the local Hawai'i outpatient antibiogram collected from a large private laboratory in Hawai'i in 2014 and the current Infectious Disease Society of America guidelines. This study may be helpful in guiding empiric treatment of SSTIs suspected to be caused by .
是一种在皮肤科患者中引起皮肤和软组织感染（SSTIs）的病原体。自1987年以来，皮肤科文献中报道的耐甲氧西林（MRSA）的发生率不断上升。本报告概述了夏威夷一家门诊办公室中甲氧西林敏感（MSSA）和MRSA的抗生素敏感性。这是一项通过回顾2012年至2014年病历进行的回顾性研究。对人口统计学、感染的解剖部位、临床诊断和抗菌药物敏感性模式进行了分析和比较。在66个样本中，57%为男性，43%为女性。在脓疱病、毛囊炎、疖以及继发感染的银屑病中更常见，且多位于四肢。MSSA占病例的73%（48例），MRSA占病例的27%（18例）。对门诊所有培养物最有效的抗生素是利奈唑胺（100%）、复方新诺明（95%）和四环素（94%）。利奈唑胺（100%）、复方新诺明（100%）对MRSA分离株最有效。我们的（此处原文缺失相关内容）和MRSA抗菌药物敏感性结果与2014年从夏威夷一家大型私人实验室收集的当地夏威夷门诊抗菌谱以及美国传染病学会目前的指南相似。这项研究可能有助于指导疑似由（此处原文缺失相关内容）引起的SSTIs的经验性治疗。
