亚临床甲癣：在HIV阳性人群中不存在吗？
Subclinical Onychomycosis: Not Present in HIV-Positive Population?
作者信息
Contreras-Rivera Claudia, Toussaint-Caire Sonia, Fernández-Martínez Ramón, Moreno-Coutiño Gabriela
机构信息
Mycology Department, General Hospital Dr. Manuel Gea González, Mexico City, Mexico.
Dermatology Service, General Hospital Dr. Manuel Gea González, Mexico City, Mexico.
出版信息
Skin Appendage Disord. 2019 Apr;5(3):155-157. doi: 10.1159/000494459. Epub 2018 Nov 21.
BACKGROUND
Onychomycosis is one of the most common nail diseases and constitutes up to 50% of all nail conditions. It is a chronic fungal nail infection common in the HIV-infected population. Few studies have found fungal organisms in the nail without clinical evidence, and thus, termed subclinical onychomycosis.
OBJECTIVES
We analyzed the nails of the HIV population in our hospital, searching for subclinical onychomycosis.
METHOD
A distal nail clipping was stained with PAS and observed by a trained dermatopathologist.
RESULTS
All of our samples ( = 48) turned out to be negative for fungal structures.
CONCLUSIONS
The epidemiology of onychomycosis is changing, treatment options are much better now, and diagnosis and infection detection are being done earlier. Therefore, we will continue to further study this disease in other patient populations so that we can compare our results and see whether the incidence of onychomycosis in the HIV population is now similar to that in those without HIV infection of the same age.
背景
甲癣是最常见的指甲疾病之一，占所有指甲病症的50%。它是一种慢性真菌性指甲感染，在艾滋病毒感染人群中很常见。很少有研究在没有临床证据的情况下在指甲中发现真菌生物体，因此称为亚临床甲癣。
目的
我们分析了我院艾滋病毒感染者的指甲，以寻找亚临床甲癣。
方法
取远端指甲剪进行PAS染色，由训练有素的皮肤病理学家观察。
结果
我们所有的样本（n = 48）真菌结构检测均为阴性。
结论
甲癣的流行病学正在发生变化，现在的治疗选择更好，诊断和感染检测也更早进行。因此，我们将继续在其他患者群体中进一步研究这种疾病，以便我们能够比较结果，看看艾滋病毒感染人群中甲癣的发病率现在是否与同年龄未感染艾滋病毒的人群相似。
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