Govaert Geertje A M, Termaat M Frank, Glaudemans A W J M, Geurts J A P, de Jong T, de Jong V M, Joosse P, Kooijmans H, Overbosch J, Scheper H, Spijkerman I J B
UMC Utrecht, afd. Traumachirurgie, Utrecht.
Contact: G.A.M. Govaert (
Ned Tijdschr Geneeskd. 2019 Apr 11;163:D3178.
Fracture-related infection (FRI) is a serious complication after fracture care and can lead to severe morbidity with loss of quality of life, a significant increase in medical expenses and loss of participation in work and social life. Early recognition, adequate surgical debridement, deep uncontaminated tissue cultures with (if indicated) soft tissue reconstruction and fracture stabilization followed by antibiotic therapy are the cornerstones of the successful management of FRI. Recently, in 2018, the AO/EBJIS consensus definition for FRI was published and both national and international working groups are being assembled and provide guidelines and tools for the care of patients with FRI. This paper is a synopsis of the Dutch guideline on FRI (2018), illustrated by a clinical case, and is aiming to provide an overview of the current knowledge on diagnosis and treatment of this disease.
骨折相关感染（FRI）是骨折治疗后的一种严重并发症，可导致严重的发病率，生活质量下降，医疗费用大幅增加，以及无法参与工作和社会生活。早期识别、充分的手术清创、深部未受污染组织培养（如有指征）、软组织重建和骨折固定，随后进行抗生素治疗，是成功治疗FRI的基石。最近，在2018年，AO/EBJIS关于FRI的共识定义发布，国家和国际工作组正在组建，并为FRI患者的护理提供指南和工具。本文是荷兰FRI指南（2018年）的概要，并通过一个临床病例进行说明，旨在概述目前关于该疾病诊断和治疗的知识。
