Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka, 565-0871, Japan.
Angew Chem Int Ed Engl. 2019 Jun 24;58(26):8907-8911. doi: 10.1002/anie.201904971. Epub 2019 May 16.
The preparation of some hypervalent iodine reagents containing a transferable amino group derived from benzophenone imine derivatives is reported. The reagents can be readily prepared and stored as a bench-stable solid, and were successfully used in the transition-metal-free oxidative amination of silyl ketene acetals to afford the corresponding α-amino esters, the benzophenone imine moieties of which could be easily hydrolyzed, thereby leading to the formation of primary amines.
本文报道了一些含有可转移氨基的高价碘试剂的制备，该氨基来源于二苯甲酮亚胺衍生物。这些试剂可以很容易地制备和储存为稳定的固体，并且成功地用于无过渡金属条件下硅基烯酮缩醛的氧化氨化反应，得到相应的α-氨基酸酯，其中的二苯甲酮亚胺部分可以很容易地水解，从而形成伯胺。
