Wei Fan-Qin, Wen Lanying, Chen Kaitian, Liu Min, Wu Xuan
a Department of Otorhinolaryngology Head and Neck Surgery , the First Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.
b Department of ENT , Sun Yat-sen University First Affiliated Hospital , Guangzhou , China.
Acta Otolaryngol. 2019 Jul;139(7):598-603. doi: 10.1080/00016489.2019.1605195. Epub 2019 May 3.
Inner ear hemorrhage is increasingly recognized as a cochlear lesion that can cause profound sudden sensorineural hearing loss (SSNHL). To investigate changes of cochlear and vestibular function and to compare therapeutic recovery from profound SSNHL induced by different etiologies. Eighty patients with profound SSNHL (≥90 dB) were divided into an inner ear hemorrhage group and a non-inner ear hemorrhage group by MRI. Statistical analysis was performed to compare the therapeutic effects from vertigo and hearing loss and the outcomes of follow-up in the two groups. There were significant differences between the two groups in terms of the overall 14-day therapeutic response rate (20 vs. 48%), the incidence of imbalance (26.7 vs. 6%), the incidence of semicircular canal dysfunction on the affected side (60 vs. 20%), the incidence of abnormal C-VEMP and O-VEMP on the affected side (63.3 vs. 38%; and 60 vs. 30%, respectively), the average hearing threshold (74.2 ± 10.7 vs. 53.6 ± 11.4 dB), and the word recognition score (65.5 ± 21.7 vs. 83.5 ± 24.5%) at a 12-month follow-up. A higher percentage of patients with profound SSNHL induced by inner ear hemorrhage were associated with vertigo and had a poor prognosis.
内耳出血越来越被认为是一种可导致严重突发性感音神经性听力损失（SSNHL）的耳蜗病变。为了研究耳蜗和前庭功能的变化，并比较不同病因引起的严重SSNHL的治疗恢复情况。80例严重SSNHL（≥90dB）患者通过MRI分为内耳出血组和非内耳出血组。进行统计分析以比较两组在眩晕和听力损失方面的治疗效果以及随访结果。两组在14天总体治疗有效率（20%对48%）、失衡发生率（26.7%对6%）、患侧半规管功能障碍发生率（60%对20%）、患侧C-VEMP和O-VEMP异常发生率（分别为63.3%对38%；60%对30%）、12个月随访时的平均听力阈值（74.2±10.7对53.6±11.4dB）以及单词识别得分（65.5±21.7对83.5±24.5%）方面存在显著差异。内耳出血引起的严重SSNHL患者中，眩晕相关比例更高，预后较差。
