Li Dan, Lin Shi-Bin, Cheng Biao
1 Department of Plastic Surgery, Southern Medical University, Guangzhou, Guangdong, China.
2 Department of Ophthalmology, Joint Shantou International Eye Center of Shantou University and Chinese University of Hong Kong, Shantou, Guangdong, China.
Photobiomodul Photomed Laser Surg. 2019 Apr;37(4):244-247. doi: 10.1089/photob.2018.4580.
Ultrapulse CO laser has been used for several decades for removal of xanthelasma lesions. However, most studies to date have focused on Caucasian patients (skin types I-II). We sought to assess the efficacy and complications of CO laser therapy for xanthelasma palpebrarum (XP) in Chinese patients (skin types III-IV). Data of 38 patients with xanthelasma who received CO laser treatment between December 2013 and January 2016 at our hospital were retrospectively analyzed. Patients were followed up for 9 months. Recurrence occurred in 19/38 (50%) patients. Recurrence was significantly more common in patients with multiple lesions (15/24; 62.5%) than in patients with single lesions (4/14; 28.6%). At 3 months after treatment, the complication rate was 63.16%. The complications included hypopigmentation (23/24; 95.8%) and scarring (1/24; 4.2%). In all patients, the hypopigmentation had disappeared by end of the 9-month follow-up. Ultrapulse CO laser appears to be capable of completely removing XP in patients with medium skin type III-IV. The most common complication is hypopigmentation, but this resolves with time.
超脉冲CO激光已用于去除睑黄瘤病变数十年。然而，迄今为止大多数研究都集中在白种人患者（皮肤类型I-II）。我们试图评估CO激光治疗中国患者（皮肤类型III-IV）睑黄瘤（XP）的疗效和并发症。回顾性分析了2013年12月至2016年1月在我院接受CO激光治疗的38例睑黄瘤患者的数据。对患者进行了9个月的随访。19/38（50%）例患者出现复发。多发病变患者（15/24；62.5%）的复发明显比单发病变患者（4/14；28.6%）更常见。治疗后3个月，并发症发生率为63.16%。并发症包括色素减退（23/24；95.8%）和瘢痕形成（1/24；4.2%）。在所有患者中，色素减退在9个月随访结束时消失。超脉冲CO激光似乎能够完全去除皮肤类型为III-IV的中度患者的XP。最常见的并发症是色素减退，但这会随时间消退。
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