Clark Hayley, Jones Mark, Shannon Debbie, Sisson Toni, Plank Ashley, Middleton Mark
Radiation Oncology Queensland, Toowoomba, Australia.
Radiation Oncology Queensland, Cairns, Australia.
J Med Imaging Radiat Sci. 2013 Jun;44(2):87-91. doi: 10.1016/j.jmir.2012.11.004. Epub 2013 Jan 1.
Online image-guided radiation therapy (IGRT) is used for all radical pelvic patients at Radiation Oncology Queensland. One linear accelerator is equipped with megavoltage electronic portal imaging. Daily imaging on this linear accelerator introduces a dose burden that must be accounted for in the planning process. This dose burden is further complicated by postintervention images taken to verify field placement corrections. Analysis of setup errors and number and management of isocenter shifts was also used to identify an appropriate dose burden to be applied.
The IGRT data of 50 radical pelvic patients were retrospectively collected and analysed, and the number of isocenter moves made was assessed. Statistical analysis of systematic and random errors, both preintervention and postintervention, was undertaken. Inclusive in this analysis was the number of times postintervention images revealed an error in manually entered isocenter shifts. The imaging dose used was also investigated.
Online IGRT was able to reduce the setup error to <2 mm for all orthogonal planes. Postintervention imaging was shown to be necessary to assess field placement, because manual errors in field placement were found to occur. The generic dose burden in use was found to be excessive.
Daily IGRT is now considered an essential tool in modern radiation therapy. Postintervention imaging is required to ensure correct isocenter placement on linear accelerators where the process is manual. The current estimate of the worst-case scenario dose burden may be reduced to either incorporate a "population" dose or a more realistic absolute maximum dose. Any removal of a quality assurance process such as this requires evidence, consultation, and careful consideration.
在线图像引导放射治疗(IGRT)应用于昆士兰放射肿瘤学中心所有接受根治性盆腔放疗的患者。一台直线加速器配备了兆伏级电子门静脉成像设备。在这台直线加速器上进行的每日成像会带来剂量负担,在治疗计划过程中必须予以考虑。干预后拍摄的用于验证射野位置校正的图像使这种剂量负担更加复杂。还通过分析摆位误差以及等中心移位的次数和管理情况来确定应施加的合适剂量负担。
回顾性收集并分析了50例接受根治性盆腔放疗患者的IGRT数据,并评估了等中心移动的次数。对干预前和干预后的系统误差和随机误差进行了统计分析。该分析还包括干预后图像显示手动输入等中心移位存在误差的次数。同时对所使用的成像剂量进行了研究。
在线IGRT能够将所有正交平面的摆位误差降低至<2毫米。结果表明,干预后成像对于评估射野位置是必要 的,因为发现存在射野位置的人为误差。发现目前使用的一般剂量负担过高。
如今,每日IGRT被视为现代放射治疗中的一项重要工具。对于手动操作的直线加速器,需要进行干预后成像以确保等中心位置正确。最坏情况剂量负担的当前估计值可以降低,要么纳入“群体”剂量,要么采用更实际的绝对最大剂量。取消任何此类质量保证程序都需要有证据、进行磋商并慎重考虑。