Roy-Byrne P P, Rubinow D R, Hoban M C, Grover G N, Blank D
Am J Psychiatry. 1987 Apr;144(4):480-4. doi: 10.1176/ajp.144.4.480.
The thyroid-stimulating hormone (TSH) and prolactin responses to thyrotropin-releasing hormone (TRH), administered during the follicular and luteal phases of the menstrual cycle, were examined in 14 women with prospectively confirmed premenstrual syndrome and in nine control subjects. There were no differences in basal or maximum increase in TSH or prolactin values between menstrual cycle phases in patients or in control subjects or between patients and control subjects in either phase. However, there was significantly greater variability in TSH response to TRH among symptomatic patients (seven of 10 patients: three with blunted and four with augmented response) than among control subjects (none of nine patients).
对14名经前瞻性确诊患有经前综合征的女性和9名对照受试者，检测了在月经周期的卵泡期和黄体期给予促甲状腺激素释放激素（TRH）后促甲状腺激素（TSH）和催乳素的反应。患者或对照受试者在月经周期各阶段之间，以及在任一阶段的患者与对照受试者之间，TSH或催乳素值的基础值或最大增加值均无差异。然而，有症状患者中TSH对TRH反应的变异性（10名患者中的7名：3名反应迟钝，4名反应增强）显著大于对照受试者（9名患者中无）。
