Oral Medicine, Department of Diagnosis and Surgery, Araraquara Dental School, São Paulo State University (Unesp), Araraquara, São Paulo, Brazil; Oral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo, Ribeirão Preto, SP, Brazil.
Oral Medicine, Department of Diagnosis and Surgery, Araraquara Dental School, São Paulo State University (Unesp), Araraquara, São Paulo, Brazil.
Oral Oncol. 2019 Jun;93:116-119. doi: 10.1016/j.oraloncology.2019.04.015. Epub 2019 Apr 30.
Myoepithelial carcinomas of the head and neck are often located in the major salivary glands, notably in the parotid glands, being less frequent in the minor salivary glands. Noteworthy, myoepithelial carcinoma in the maxillary sinus is extremely rare. In fact, only five cases have been previously published to date. Here, we present, for the first time, a detailed immunohistochemical and in situ hybridization analysis of a SMARCB1 (INI-1)-intact myoepithelial carcinoma with rhabdoid features, expanding the histopathological spectrum of high-grade sinonasal carcinomas.
头颈部肌上皮癌通常位于大涎腺，特别是腮腺，而在小涎腺中则较少见。值得注意的是，上颌窦的肌上皮癌极为罕见。实际上，迄今为止仅发表了 5 例。在这里，我们首次详细介绍了一例具有横纹肌样特征且 SMARCB1（INI-1）完整的肌上皮癌的免疫组织化学和原位杂交分析，扩大了高级鼻旁窦癌的组织病理学谱。
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