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上颌窦高级别肌上皮癌伴广泛横纹肌样分化及 INI-1 缺失:扩大了鼻窦癌的组织病理学谱。

High Grade Myoepithelial Carcinoma of Maxillary Sinus with Extensive Rhabdoid Differentiation and INI-1 Loss: Expanding the Histopathological Spectrum of Sinonasal Carcinoma.

机构信息

Department of Histopathology and Cytopathology, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, 110085, India.

Department of Radiology, Rajiv Gandhi Cancer Institute & Research Centre, Delhi, 110085, India.

出版信息

Head Neck Pathol. 2022 Sep;16(3):876-880. doi: 10.1007/s12105-021-01397-3. Epub 2021 Dec 8.

Abstract

Myoepithelial carcinoma (MEC) of salivary gland is an uncommon tumor with no specific age or sex predilection. Most of the cases (~90%) arise in parotid and submandibular glands followed by palate. MEC of maxillary sinus is rare. We describe an extremely rare case of high grade MEC with rhabdoid differentiation and INI-1 loss involving maxillary sinus of an elderly male.

摘要

涎腺肌上皮癌(MEC)是一种不常见的肿瘤,无特定的年龄或性别倾向。大多数病例(约 90%)发生在腮腺和颌下腺,其次是腭部。上颌窦 MEC 非常罕见。我们描述了一例非常罕见的高级别 MEC,具有横纹肌样分化和 INI-1 缺失,累及老年男性的上颌窦。

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