Department of Medicine, University of Otago, Dunedin, New Zealand.
National Kidney Foundation of Samoa, Apia, Samoa.
Semin Nephrol. 2019 May;39(3):297-299. doi: 10.1016/j.semnephrol.2019.03.001.
Chronic kidney disease (CKD) disproportionately affects Māori (the indigenous people of New Zealand [NZ]) as well as Pacific people, particularly from Samoa, Tonga, and Fiji. As New Zealand is home to the largest population of Pacific people, New Zealand and the Pacific Islands fulfil the definition of a CKD 'hotspot'. Although diabetic nephropathy is the major cause of CKD, with disproportionately higher rates in NZ Māori and Pacific people, there is increasing evidence that there is a familial predisposition to CKD that is not due to diabetes. Further studies are required to understand the reasons for this pre-disposition.
慢性肾脏病（CKD）在毛利人（新西兰的土著民族）和太平洋岛民中发病率不成比例，尤其是萨摩亚人、汤加人和斐济人。由于新西兰是太平洋地区人口最多的国家，因此新西兰和太平洋岛屿符合 CKD“热点”的定义。虽然糖尿病肾病是 CKD 的主要病因，新西兰毛利人和太平洋岛民的发病率更高，但越来越多的证据表明，CKD 存在家族易感性，而不是由糖尿病引起的。需要进一步的研究来了解这种易感性的原因。
