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[瓣膜手术中的再次手术。基于194例病例]

[Reoperations in valve surgery. Apropos of 194 cases].

作者信息

Jegaden O, Rumolo A, Bonnefoy J Y, Devolfe C, Coll-Mazzei J, Mikaeloff P

出版信息

Arch Mal Coeur Vaiss. 1986 Nov;79(12):1688-94.

PMID:3105480
Abstract

Between 1970 and 1985, 194 patients underwent one or several reoperations after conservative valvular surgery (Group A) or valvular replacement surgery (Group B). Group A: comprised 141 patients with a previous history of closed heart mitral commissurotomy (114 cases), open heart mitral commissurotomy (20 cases), mitral valvuloplasty (5 cases) or aortic commissurotomy (2 cases) reoperated after an average period of 153 +/- 44 months. At reoperation, prosthetic valve replacement of the previously operated valve was systematic and another valvular procedure was also performed in 66 cases. Hospital mortality was 7.8 p. 100. Mortality was high in patients reoperated in functional Class IV of the NYHA classification, after closed heart mitral commissurotomy performed over 10 years before hand. The global mortality rate was 17 p. 100 (average postoperative follow-up of 70 +/- 44 months). The actuarial 5 year survival rate was 85 +/- 6 p. 100 and the 10 year survival was 70 +/- 13 p. 100; NYHA Class IV cardiac failure was a significant poor prognostic factor (p less than 0.05). The prognosis of reoperation after commissurotomy depended mainly on the interval between the relapse of symptoms and reoperation. Group B: comprised 53 patients with valvular prostheses reoperated after an average period of 58 +/- 41 months. The indications of reoperation were prosthetic valve dysfunction (31 cases), perivalvular leak (5 cases), prosthetic valve thrombosis (6 cases), infective endocarditis (7 cases), haemolysis (1 case) and associated valvular disease (10 cases). Reoperation concerned mechanical prostheses in 26 cases and bioprostheses in 24 cases. It consisted in valvular replacement (51 cases) or reinsertion (2 cases). Eight patients underwent second reoperation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1970年至1985年间,194例患者在接受保守性瓣膜手术(A组)或瓣膜置换手术(B组)后进行了一次或多次再次手术。A组:包括141例患者,他们既往有闭式二尖瓣交界切开术史(114例)、直视二尖瓣交界切开术史(20例)、二尖瓣成形术史(5例)或主动脉交界切开术史(2例),平均153±44个月后进行再次手术。再次手术时,对先前手术的瓣膜进行人工瓣膜置换是常规操作,66例患者还进行了另一项瓣膜手术。医院死亡率为7.8%。在纽约心脏协会(NYHA)心功能IV级患者中,若在10多年前进行闭式二尖瓣交界切开术后再次手术,死亡率较高。总体死亡率为17%(术后平均随访70±44个月)。5年精算生存率为85±6%,10年生存率为70±13%;NYHA心功能IV级心力衰竭是一个显著的不良预后因素(p<0.05)。交界切开术后再次手术的预后主要取决于症状复发与再次手术之间的间隔时间。B组:包括53例人工瓣膜患者,平均58±41个月后进行再次手术。再次手术的指征包括人工瓣膜功能障碍(31例)、瓣周漏(5例)、人工瓣膜血栓形成(6例)、感染性心内膜炎(7例)、溶血(1例)和相关瓣膜疾病(10例)。再次手术涉及26例机械瓣膜和24例生物瓣膜。手术方式包括瓣膜置换(51例)或重新植入(2例)。8例患者接受了二次再次手术。(摘要截断于250字)

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