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[永久性心房特异性刺激。65例随访1至5年的临床经验]

[Exclusive permanent atrial stimulation. Clinical experience apropos of 65 cases with a follow-up of 1 to 5 years].

作者信息

Barnay C, Coste A, Quittet F, Medvedowsky J L

出版信息

Arch Mal Coeur Vaiss. 1986 Nov;79(12):1703-10.

PMID:3105482
Abstract

The authors report their experience of permanent exclusive atrial pacing in the treatment of sinus node dysfunction in a series of 65 cases with a follow up of 1 to 5 years (average 37.6 months; 2406 patients months), 41 women and 24 men aged 74 +/- 3 years. Sixty one patients were symptomatic. The diagnosis was made from surface ECG recordings in 54 cases (83 p. 100) and after electrophysiological investigation in 11 cases (16 p. 100). Atrioventricular conduction was carefully evaluated before implantation: PR equal to or less than 200 ms, Wenckebach point equal to or greater than 130/min, absence of ventricular pauses longer than 3,000 ms after carotid sinus massage, HV interval equal to or less than 55 ms [measured in 57 cases (87 p. 100)], negative Ajmaline test in 6 patients with intraventricular conduction defects. Performed J-shaped atrial leads with active (66 p. 100) or passive fixations (34 p. 100) were implanted by an endocavitary approach (right subclavian vein in 60 cases: 92 p. 100). There were 3 cases of early lead displacement and one patient developed an elevated threshold of pacing. There were 5 deaths during the follow-up period (3 of cardiovascular origin). The neurological symptoms disappeared in 93 p. 100 of cases. No cases of cardiac failure were observed after permanent pacing. Fifteen patients had documented supraventricular arrhythmias before implantation; 5 patients continued to have the same paroxysmal or permanent arrhythmias but 10 patients had no further recurrences, 8 with and 2 without antiarrhythmic therapy.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

作者报告了他们应用永久性单纯心房起搏治疗窦房结功能障碍的经验,共65例,随访1至5年(平均37.6个月;2406患者月),41例女性和24例男性,年龄74±3岁。61例患者有症状。54例(83%)根据体表心电图记录确诊,11例(16%)经电生理检查确诊。植入前仔细评估房室传导:PR等于或小于200毫秒,文氏点等于或大于130次/分钟,颈动脉窦按摩后无长于3000毫秒的心室停搏,HV间期等于或小于55毫秒[57例(87%)测量],6例室内传导阻滞患者阿马林试验阴性。采用心腔内途径(60例经右锁骨下静脉:92%)植入J形心房电极,其中主动固定(66%)或被动固定(34%)。有3例早期电极移位,1例患者起搏阈值升高。随访期间有5例死亡(3例心血管原因)。93%的病例神经症状消失。永久起搏后未观察到心力衰竭病例。15例患者植入前有记录的室上性心律失常;5例患者继续有相同的阵发性或永久性心律失常,但10例患者未再复发,8例接受抗心律失常治疗,2例未接受治疗。(摘要截短至250字)

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