Léon Bérard Cancer Centre, 28 rue Laennec, 69008 Lyon, France; Cancer Research Centre of Lyon, UMR Inserm 1052 CNRS 5286 Centre Léon Bérard, 69008 Lyon, France.
Section of Cancer Surveillance, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69008 Lyon, France.
Cancer Epidemiol. 2019 Jun;60:216-220. doi: 10.1016/j.canep.2019.02.009. Epub 2019 May 2.
Insufficient physical activity is a known risk factor for various co-morbidities, including cancer. Globally, its prevalence has increased markedly over the past decades. The aim of this study was to estimate the proportion and number of cancers that were attributable to insufficient physical activity in France in 2015.
Population attributable fractions (PAFs) and numbers of cancer cases attributable to insufficient physical activity (<30 min daily of moderate-to-vigorous physical activity) were estimated by age, sex and cancer site. Assuming a 10-year lag-period, PAFs were calculated using physical activity prevalence from a cross-sectional French population survey and cancer-specific relative risks.
About half of all French adults were found to be insufficiently physically active, with great variation by age and sex. In 2015, an estimated 2973 cancer cases diagnosed in French adults aged 30y+ were attributable to insufficient physical activity, corresponding to 0.8% of all cancer cases (0.2% in men and 1.6% in women). This comprised 3.8% of all postmenopausal breast cancers (1620 cases), 3.6% of all colon cancers (902 cases) and 6.0% of all cancers of the corpus uteri (450 cases). If at least half of the recommended physical activity level was achieved, 1095 cancer cases could have been avoided.
Insufficient physical activity is associated to about 3000 cancer cases in France, a country with comparatively low but increasing prevalence of this risk factor. This result is important for setting priorities in cancer prevention programmes aiming to increase physical activity in France and Europe in general.
身体活动不足是多种合并症的已知危险因素，包括癌症。在过去几十年中，全球身体活动不足的患病率显著增加。本研究的目的是估计 2015 年法国因身体活动不足而导致的癌症比例和数量。
通过年龄、性别和癌症部位，估计身体活动不足（每天进行<30 分钟的中等至剧烈身体活动）的比例和归因于癌症的病例数。假设存在 10 年的滞后期，使用来自法国横断面人群调查的身体活动流行率和癌症特异性相对风险来计算人群归因分数（PAF）。
约一半的法国成年人身体活动不足，且年龄和性别差异很大。2015 年，估计有 2973 例 30 岁及以上法国成年人被诊断患有癌症归因于身体活动不足，占所有癌症病例的 0.8%（男性占 0.2%，女性占 1.6%）。这包括 3.8%的绝经后乳腺癌（1620 例）、3.6%的结肠癌（902 例）和 6.0%的子宫体癌（450 例）。如果至少达到一半的推荐身体活动水平，则可以避免 1095 例癌症病例。
在法国，身体活动不足与约 3000 例癌症有关，该国的这一风险因素的流行率虽然相对较低，但呈上升趋势。这一结果对于制定旨在提高法国和整个欧洲身体活动水平的癌症预防计划的优先事项非常重要。
