BerbeeWalsh Department of Emergency Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Cardiovascular Center of Tampa, Florida Hospital Tampa, Tampa, Florida.
Am J Cardiol. 2019 Jul 1;124(1):39-43. doi: 10.1016/j.amjcard.2019.03.046. Epub 2019 Apr 9.
The incremental benefit of emergency medical services (EMS) activation of the cardiac catheterization laboratory (CCL) for ST-elevation myocardial infarction (STEMI) in the setting of an established in-house interventional team (IHIT) is uncertain. We evaluated the impact of EMS activation on door-to-balloon (D2B) time and first medical contact-to-balloon (FMC2B) time for STEMI when coupled with a 24-hour/day IHIT. All patients presenting with STEMI to Loyola University Medical Center had demographic, procedural, and outcome data consecutively entered in a STEMI Data Registry. From 223 consecutive patients presenting between April 2009 and December 2015, a retrospective analysis was performed on 190 patients. Patients were divided into 2 groups depending on CCL activation mode (EMS activation or emergency department activation) and STEMI treatment process times were compared. The primary end point was D2B process times. The secondary end point was FMC2B process times in a subgroup analysis of EMS-transported patients. D2B times were shorter (37 ± 14 minutes vs 57 ± 27 minutes, p < 0.001) with EMS activation. Subgroup analysis of EMS-transported patients demonstrated shorter FMC2B times with EMS activation (52 ± 17 minutes vs 67 ± 32 minutes, p = 0.002). EMS activation was the only predictor of D2B ≤60 minutes in multivariable analysis of EMS-transported patients (odds ratio 9.4; 95% confidence interval 2.1 to 43.0; p = 0.04). In conclusion, EMS activation of the CCL in STEMI was associated with significant improvements in already excellent D2B and FMC2B times even in the setting of a 24-hour/day IHIT.
在已经建立了院内介入团队(IHIT)的情况下,对于 ST 段抬高型心肌梗死(STEMI),急诊医疗服务(EMS)激活心脏导管室(CCL)的增量效益尚不确定。我们评估了在 24 小时/天 IHIT 的情况下,与 EMS 激活相结合时,对 STEMI 的门到球囊(D2B)时间和首次医疗接触到球囊(FMC2B)时间的影响。所有在洛约拉大学医学中心就诊的 STEMI 患者都有连续输入 STEMI 数据登记册的人口统计学、程序和结果数据。在 2009 年 4 月至 2015 年 12 月期间连续就诊的 223 例患者中,对 190 例患者进行了回顾性分析。根据 CCL 激活模式(EMS 激活或急诊部激活)将患者分为 2 组,并比较 STEMI 治疗过程时间。主要终点是 D2B 过程时间。在 EMS 转运患者的亚组分析中,次要终点是 FMC2B 过程时间。与 EMS 激活相比,D2B 时间更短(37 ± 14 分钟比 57 ± 27 分钟,p<0.001)。EMS 转运患者的亚组分析显示,EMS 激活时 FMC2B 时间更短(52 ± 17 分钟比 67 ± 32 分钟,p=0.002)。在 EMS 转运患者的多变量分析中,EMS 激活是 D2B≤60 分钟的唯一预测因素(优势比 9.4;95%置信区间 2.1 至 43.0;p=0.04)。总之,即使在 24 小时/天 IHIT 的情况下,STEMI 中 CCL 的 EMS 激活与已经出色的 D2B 和 FMC2B 时间的显著改善相关。