Department of Neurosurgery, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo 1878551, Japan; Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama 2360004, Japan.
Department of Pediatrics, Graduate School of Medicine, Yokohama City University, Yokohama 2360004, Japan; Department of Pediatrics, Wayne State University, Children's Hospital of Michigan, Detroit, MI 48201, USA.
Clin Neurophysiol. 2019 Aug;130(8):1446-1454. doi: 10.1016/j.clinph.2019.04.008. Epub 2019 Apr 22.
To characterize the spatiotemporal dynamics of auditory and picture naming-related cortical activation in Japanese-speaking patients.
Ten patients were assigned auditory naming and picture naming tasks during extraoperative intracranial EEG recording in a tertiary epilepsy center. Time-frequency analysis determined at what electrode sites and at what time windows during each task the amplitude of high-gamma activity (65-95 Hz) was modulated.
The superior-temporal gyrus on each hemisphere showed high-gamma augmentation during sentence listening, whereas the left middle-temporal and inferior-frontal gyri showed high-gamma augmentation peaking around stimulus offset. Auditory naming-specific high-gamma augmentation was noted in the bilateral superior-temporal gyri as well as left frontal-parietal-temporal perisylvian network regions, whereas picture naming-specific augmentation was noted in the occipital-fusiform regions, bilaterally. The inferior pre- and postcentral gyri on each hemisphere showed modality-common high-gamma augmentation time-locked to overt responses.
The spatiotemporal dynamics of auditory and picture naming-related high-gamma augmentation in Japanese-speaking patients were qualitatively similar to those previously reported in studies of English-speaking patients.
The cortical dynamics for auditory sentence recognition are at least partly shared by cohorts speaking two distinct languages. Multicenter studies regarding the clinical utility of high-gamma language mapping across Eastern and Western hemispheres may be feasible.
描述日语患者听觉和图片命名相关皮质激活的时空动力学。
在一家三级癫痫中心的术中颅内 EEG 记录期间，10 名患者被分配进行听觉命名和图片命名任务。时频分析确定在每个任务中，高伽马活动（65-95Hz）的振幅在哪个电极位置和时间窗口被调制。
每个半球的颞上回在句子听时表现出高伽马增强，而左侧颞中回和额下回在刺激结束时表现出高伽马增强峰值。听觉命名特异性高伽马增强在双侧颞上回以及左侧额顶颞岛叶网络区域可见，而图片命名特异性增强在枕叶梭状回区域可见。每个半球的下前和后中央回表现出与显性反应锁时的模态共有高伽马增强。
日语患者听觉和图片命名相关高伽马增强的时空动力学与之前英语患者研究中报告的定性相似。
听觉句子识别的皮质动力学至少部分由两种不同语言的队列共享。跨东西方半球进行高伽马语言映射的临床效用的多中心研究可能是可行的。
