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三级眼科中心通过光学相干断层扫描诊断的葡萄膜炎黄斑水肿模式

Patterns of Macular Edema in Uveitis as Diagnosed by Optical Coherence Tomography in Tertiary Eye Center.

作者信息

Gupta Sharad, Shah Dev Narayan, Joshi Sagun Narayan, Aryal Manoj, Puri Lila Raj

机构信息

Sagarmatha Choudhary Eye Hospital, Siraha, Lahan.

出版信息

Nepal J Ophthalmol. 2018 Jan;10(19):39-46. doi: 10.3126/nepjoph.v10i1.21687.

DOI:10.3126/nepjoph.v10i1.21687
PMID:31056575
Abstract

AIM

The aim of the study is to classify the patterns of uveitic macular edema using Optical Coherence Tomography as a diagnostic tool.

METHODOLOGY

It is the Descriptive, cross-sectional study. All patients fulfilling the diagnostic criteria with Optical coherence tomography diagnosed macular edema were enrolled from 1 January 2012 to 30 June 2013. Patterns of uveitic macular edema were classified.

RESULTS

A total of 65 eyes of 47 patients were included. Twenty eight (59.57%) were male. The male to female ratio was 1.5:1. The mean age was 38 years (SD 14.68). Twenty nine patients (61.71%) had unilateral involvement and 18 (38.29%) had bilateral involvement. Forty five eyes of 33 cases (69.23%, 70.21%) had intermediate uveitis, followed by 10 eyes of 7 cases (15.38, 14.9%) of posterior uveitis, 6 eyes of 5 cases (9.23%, 10.63 %) of anterior uveitis and 4 eyes of 2 cases (6.16%,4.2%) of pan-uveitis. Patterns of macular edema were classified: diff use macular edema (DME), cystoid macular edema (CME) and serous retinal detachment (SRD) of which 35 (53.84%) eyes had CME. The etiological diagnosis was found in 7(14.90 %) out of 47 patients.

CONCLUSION

A significant percentage of cases were idiopathic. Macular edema may go unnoticed unless OCT is performed. Macular detachment is an important feature of macular edema that affects visual acuity and is not readily detected by Fundus Fluorescein Angiography (FFA). Optical coherence tomography (OCT) is safe and non-invasive technique and has the potential for measuring changes in retinal thickness and axial extent of edema.

摘要

目的

本研究旨在利用光学相干断层扫描作为诊断工具,对葡萄膜炎性黄斑水肿的模式进行分类。

方法

这是一项描述性横断面研究。2012年1月1日至2013年6月30日期间,纳入所有经光学相干断层扫描诊断为黄斑水肿且符合诊断标准的患者。对葡萄膜炎性黄斑水肿的模式进行分类。

结果

共纳入47例患者的65只眼。其中男性28例(59.57%)。男女比例为1.5:1。平均年龄为38岁(标准差14.68)。29例患者(61.71%)为单眼受累,18例(38.29%)为双眼受累。33例患者的45只眼(69.23%,70.21%)患有中间葡萄膜炎,其次是7例患者的10只眼(15.38%,14.9%)患有后葡萄膜炎,5例患者的6只眼(9.23%,10.63%)患有前葡萄膜炎,2例患者的4只眼(6.16%,4.2%)患有全葡萄膜炎。黄斑水肿模式分类如下:弥漫性黄斑水肿(DME)、黄斑囊样水肿(CME)和浆液性视网膜脱离(SRD),其中35只眼(53.84%)为CME。47例患者中有7例(14.90%)明确病因诊断。

结论

相当一部分病例为特发性。除非进行光学相干断层扫描,黄斑水肿可能未被注意到。黄斑脱离是黄斑水肿的一个重要特征,会影响视力,且眼底荧光血管造影(FFA)不易检测到。光学相干断层扫描(OCT)是一种安全、无创的技术,有潜力测量视网膜厚度变化和水肿的轴向范围。

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