Yue Bingbing, Zhu Liangliang
State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, 200438, China.
Chem Asian J. 2019 Jul 1;14(13):2172-2180. doi: 10.1002/asia.201900460. Epub 2019 Jun 21.
Supramolecular chirality, generated by the asymmetric assembly of chiral or achiral molecules, has attracted intense study owing to its potential to offer insights into natural biological structures and its crucial roles in advanced materials. The optical activity and stacking pathway of building molecules both greatly determine the chirality of the whole supramolecular structure. The flexibility of supramolecular structures makes their chirality easy to modulate through abundant means. Adjustment of the molecular structure or packing mode, or external stimuli that act like a finger gently pushing toy bricks, can greatly change the chirality of supramolecular assemblies. The dynamic regulation of chiral nanostructures on the intramolecular, intermolecular, and external levels could be regarded as the modulatory essence in numerous strategies, however, this perspective is ignored in most reviews in the literature. Herein, therefore, we focus on the ingenious dynamic modulation of chiral nanostructures by these factors. Through dynamic modulation with changes in chiroptical spectroscopy and electron microscopy, the mechanism of formation of supramolecular chirality is also elaborated.
由手性或非手性分子的不对称组装产生的超分子手性，因其有助于深入了解天然生物结构的潜力及其在先进材料中的关键作用而备受关注。构建分子的光学活性和堆积方式都极大地决定了整个超分子结构的手性。超分子结构的灵活性使得它们的手性易于通过多种方式进行调节。分子结构或堆积模式的调整，或像手指轻轻推动玩具积木一样的外部刺激，都能极大地改变超分子组装体的手性。手性纳米结构在分子内、分子间和外部层面的动态调控可被视为众多策略中的调控本质，然而，这一观点在文献中的大多数综述中都被忽视了。因此，在此我们重点关注这些因素对手性纳米结构的巧妙动态调控。通过随着圆二色光谱和电子显微镜的变化进行动态调控，还阐述了超分子手性的形成机制。
