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[浅针配合耳穴压丸治疗肝郁体质原发性失眠的临床试验]

[A clinical trial of treatment of primary insomnia of patients with -stagnation constitution by shallow acupuncture combined with ear-acupoint pellet-pressing].

作者信息

He Qi, Yang Yuan-Fang, Wu Cheng-Lin

机构信息

Department of Prevention and Health Care, Zhongshan Hospital of Traditional Chinese Medicine, Zhongshan 528400, Guangdong Province, China.

Department of Massage, Quanzhou Orthopedic-traumatological Hospital, Quanzhou 362000, Fujian Province.

出版信息

Zhen Ci Yan Jiu. 2019 Apr 25;44(4):293-6. doi: 10.13702/j.1000-0607.170614.

DOI:10.13702/j.1000-0607.170614
PMID:31056884
Abstract

OBJECTIVE

To investigate the clinical effect of shallow acupuncture combined with ear-acupoint pellet-pressing in the treatment of primary insomnia in patients with -stagnation constitution.

METHODS

A total of 60 primary insomnia outpatients with -stagnation constitution were randomly divided into treatment group and control group, with 30 patients in each group. The patients in the control group were given oral Alprazolam tablets once a day, and those in the treatment group given shallow acupuncture of Yintang (EX-HN3), Shangen (inferior to EX-HN3), Anmian (EX-HN16) and bilateral Xingjian (LR2) and bilateral Taichong (LR3), once a day, and combined with pellet-pressing of ear acupoints "Shenmen""Sympathy""Subcortex""Heart" and "Liver" once every other day. Each course of treatment was 10 consecutive days, and both groups were treated for three courses. The sleep quality was assessed using Pittsburgh Sleep Quality Index (PSQI), the emotional status assessed using Self-rating Depression Scale (SDS), and the -stagnation state evaluated according to "the Criteria for Classification and Judgement of Constitution of Traditional Chinese Medicine (2009)". The therapeutic effect was evaluated according to "the Criteria for Diagnosis and Evaluation of Therapeutic Effect of Diseases of Traditional Chinese Medicine"..

RESULTS

Of the two 30 cases in the control and treatment groups, 2 (6.7%) and 6 (20.0%) were cured, 6 (20.0%) and 14 (46.7%) experienced marked improvement in their symptoms, 21 (70.0%) and 6 (20.0%) were effective, and 1 (3.3%) and 4 (13.3%) ineffective, with the effective rate being 86.7% and 96.7%, respectively. No significant difference was found between the two groups in the short-term effect (>0.05). One month's follow-up showed that, of the two 30 cases in the control and treatment groups, 2 (6.7%) and 5 (16.7%) were cured, 4(13.3%) and 14 (46.6%) experienced marked improvement, 10 (33.3%) and 6 (20.0%) were effective, and 14(46.7%) and 5(16.7%) ineffective, with the effective rate being 53.3% and 83.3%, respectively. The long-term therapeutic effect of the treatment group was significantly superior to that of the control group (<0.05). After the treatment, both PSQI and SDS scores in the two groups, and -stagnation score in the treatment group showed a significant reduction in comparison with their own pretreatment (<0.05), and one-month's follow-up (not the short-term outcome) displayed that the PSQI, SDS and -stagnation scores of the treatment group were significantly lower than those of the control group (<0.05)..

CONCLUSION

Shallow acupuncture combined with ear-acupoint pellet-pressing can significantly improve sleep quality, depression symptoms, and pathological constitution in primary insomnia patients with -stagnation constitution, possessing a stable long-term clinical effect.

摘要

目的

探讨浅针配合耳穴压丸治疗肝郁体质原发性失眠的临床疗效。

方法

将60例肝郁体质原发性失眠门诊患者随机分为治疗组和对照组,每组30例。对照组患者每日口服1次阿普唑仑片,治疗组患者采用印堂(EX-HN3)、山根(EX-HN3下方)、安眠(EX-HN16)及双侧行间(LR2)、双侧太冲(LR3)浅针治疗,每日1次,并配合耳穴“神门”“交感”“皮质下”“心”“肝”压丸,隔日1次。每个疗程连续治疗10天,两组均治疗3个疗程。采用匹兹堡睡眠质量指数(PSQI)评估睡眠质量,采用自评抑郁量表(SDS)评估情绪状态,并根据《中医体质分类与判定标准(2009版)》评估肝郁状态。根据《中医病证诊断疗效标准》评价疗效。

结果

对照组30例和治疗组30例中,治愈分别为2例(6.7%)和6例(20.0%),症状明显改善分别为6例(20.0%)和14例(46.7%),有效分别为21例(70.0%)和6例(20.0%),无效分别为1例(3.3%)和4例(13.3%),有效率分别为86.7%和96.7%。两组短期疗效比较差异无统计学意义(>0.05)。1个月随访显示,对照组30例和治疗组30例中,治愈分别为2例(6.7%)和5例(16.7%),明显改善分别为4例(13.3%)和14例(46.6%),有效分别为10例(33.3%)和6例(20.0%),无效分别为14例(46.7%)和5例(16.7%),有效率分别为53.3%和83.3%。治疗组长期疗效明显优于对照组(<0.05)。治疗后,两组PSQI、SDS评分及治疗组肝郁评分与自身治疗前比较均明显降低(<0.05),1个月随访(非短期结果)显示,治疗组PSQI、SDS及肝郁评分明显低于对照组(<0.05)。

结论

浅针配合耳穴压丸能明显改善肝郁体质原发性失眠患者的睡眠质量、抑郁症状及病理体质,具有稳定的长期临床疗效。

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