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基于计算机人工智能系统的中医药非药物疗法治疗失眠症的临床疗效观察:系统评价与荟萃分析。

Observation on the Clinical Efficacy of Traditional Chinese Medicine Non-Drug Therapy in the Treatment of Insomnia: A Systematic Review and Meta-Analysis Based on Computer Artificial Intelligence System.

机构信息

Department of Nursing, Haikou Hospital of Traditional Chinese Medicine, Haikou, Hainan 570216, China.

Department of Massage, Haikou Hospital of Traditional Chinese Medicine, Haikou, Hainan 570216, China.

出版信息

Comput Intell Neurosci. 2022 Oct 11;2022:1081713. doi: 10.1155/2022/1081713. eCollection 2022.

Abstract

OBJECTIVE

Insomnia is a common and frequently occurring disease affecting the health of the population, which can seriously affect the work and life of patients. Drug treatment of insomnia has a rapid onset of action but has a large adverse reaction incidence rate. Traditional external treatment of traditional Chinese medicine (TCM) belongs to a type of non-drug therapy, the treatment of insomnia has a long history, but the methods of non-drug treatment of TCM are diverse, and the efficacy is also different. This study investigated the efficacy of TCM non-drug therapy in the treatment of insomnia by means of literature search and meta-analysis.

METHODS

We searched Embase, Pubmed, OVid, WOS, CNKI, and CBM for randomized controlled trials (RCTs) on the use of TCM as a non-drug treatment for primary insomnia. After doing a literature search according to the inclusion and exclusion criteria, we used Cochrane rob v2.0 to assess the potential for bias in the studies that were included, and we did a combined analysis and assessment of the effectiveness of the therapy.

RESULTS

16 articles were included in this study for quantitative analysis, and a total of 1285 patients participated in the study, including 643 patients in the intervention group and 642 patients in the control group. Meta-analysis showed that non-drug therapy of TCM could improve the treatment response rate of insomnia patients [ = 6.88, 95%CI (4.40,10.74),  = 8.48, < 0.0001], reduce post-treatment total score [ = -3.42, 95%CI (-4.62, -2.22),  = -5.60, < 0.0001], and improved patient anxiety [ = -1.25, 95%CI (-2.13, -0.37),  = -2.78, =0.01] and degree of depression [ = -1.53, 95%CI (-2.84, -0.21),  = -2.28, =0.02]. The heterogeneity survey showed that treatment time was one of the sources of heterogeneity. Meta-regression analysis revealed that publication year, patient age, sample size, and intervention characteristics were not specific factors affecting the combined results. . TCM non-drug therapy (acupuncture, moxibustion, massage, and auricular point pressing beans) can significantly improve the score of patients after treatment and improve the degree of anxiety and depression of patients, with significant effect, which is worthy of clinical promotion.

摘要

目的

失眠是一种常见且经常发生的疾病,影响着人群的健康,可严重影响患者的工作和生活。失眠的药物治疗起效迅速,但不良反应发生率高。传统中医的外部治疗属于非药物疗法,治疗失眠的历史悠久,但中医非药物治疗方法多样,疗效也不同。本研究通过文献检索和荟萃分析探讨了中医非药物疗法治疗失眠的疗效。

方法

我们检索了 Embase、Pubmed、Ovid、WOS、CNKI 和 CBM 中关于中医作为原发性失眠非药物治疗的随机对照试验(RCT)。根据纳入和排除标准进行文献检索后,我们使用 Cochrane rob v2.0 评估纳入研究的潜在偏倚,并对治疗效果进行联合分析和评估。

结果

本研究共纳入 16 篇文章进行定量分析,共有 1285 名患者参与研究,其中干预组 643 名,对照组 642 名。荟萃分析显示,中医非药物疗法可提高失眠患者的治疗反应率[ = 6.88,95%CI(4.40,10.74), = 8.48,<0.0001],降低治疗后总评分[ = -3.42,95%CI(-4.62,-2.22), = -5.60,<0.0001],并改善患者的焦虑[ = -1.25,95%CI(-2.13,-0.37), = -2.78,=0.01]和抑郁程度[ = -1.53,95%CI(-2.84,-0.21), = -2.28,=0.02]。异质性调查显示,治疗时间是异质性的来源之一。Meta 回归分析表明,出版年份、患者年龄、样本量和干预特征不是影响合并结果的特定因素。中医非药物疗法(针灸、艾灸、按摩、耳穴压豆)可明显改善患者治疗后的评分,改善患者的焦虑和抑郁程度,疗效显著,值得临床推广。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7201/9578844/465c62afe807/CIN2022-1081713.001.jpg

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