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接受治疗的HIV阳性黑人女性的健康心理和社会决定因素、抗逆转录病毒疗法(ART)依从性及病毒抑制情况

Psychological and social determinants of health, antiretroviral therapy (ART) adherence, and viral suppression among HIV-positive black women in care.

作者信息

Bradley Erin L P, Frazier Emma L, Carree Tamara, Hubbard McCree Donna, Sutton Madeline Y

机构信息

a Division of HIV/AIDS Prevention , Centers for Disease Control and Prevention , Atlanta , GA , USA.

b ICF Corporation , Atlanta , GA , USA.

出版信息

AIDS Care. 2019 Aug;31(8):932-941. doi: 10.1080/09540121.2019.1612022. Epub 2019 May 6.

Abstract

Black women are disproportionately affected by HIV, accounting for 61% of women diagnosed in 2016. Black women with HIV are less likely to be adherent to antiretroviral therapy (ART) and virally suppressed compared to women of other racial/ethnic groups. We analyzed 2013-2014 data from 1703 black women patients in the Centers for Disease Control and Prevention's Medical Monitoring Project to examine whether select psychological and social determinants of health (SDH) factors were associated with ART adherence and viral suppression. We calculated weighted estimates and used multivariable logistic regression with adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) to examine correlates of ART adherence and viral suppression. Women who had not been incarcerated in the past 12 months (aPR = 1.24; CI: 1.04-1.48) and had not experienced discrimination in a health care setting since their HIV diagnosis (aPR = 1.06; 1.00-1.11) were slightly more likely to be adherent to ART. Women who lived above the federal poverty level were more likely to be virally suppressed during the past 12 months (aPR = 1.09; CI: 1.01-1.18). More research is warranted to identify the best strategies to create health care settings that encourage black women's HIV care engagement, and to address other key SDH and/or psychological factors.

摘要

黑人女性受艾滋病毒影响的比例过高,在2016年被诊断出感染艾滋病毒的女性中占61%。与其他种族/族裔群体的女性相比,感染艾滋病毒的黑人女性坚持抗逆转录病毒疗法(ART)并实现病毒抑制的可能性较小。我们分析了疾病控制与预防中心医疗监测项目中1703名黑人女性患者2013 - 2014年的数据,以研究某些健康的心理和社会决定因素(SDH)是否与ART依从性和病毒抑制相关。我们计算了加权估计值,并使用多变量逻辑回归以及调整后的患病率比值(aPR)和95%置信区间(CI)来研究ART依从性和病毒抑制的相关因素。在过去12个月内未被监禁的女性(aPR = 1.24;CI:1.04 - 1.48)以及自艾滋病毒诊断以来在医疗环境中未经历过歧视的女性(aPR = 1.06;1.00 - 1.11)坚持ART的可能性略高。生活在联邦贫困线以上的女性在过去12个月内更有可能实现病毒抑制(aPR = 1.09;CI:1.01 - 1.18)。有必要开展更多研究,以确定创造鼓励黑人女性参与艾滋病毒治疗的医疗环境的最佳策略,并解决其他关键的SDH和/或心理因素。

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