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Overuse of monitoring of blood concentrations of antiepileptic drugs.

作者信息

Chadwick D W

出版信息

Br Med J (Clin Res Ed). 1987 Mar 21;294(6574):723-4. doi: 10.1136/bmj.294.6574.723.

DOI:10.1136/bmj.294.6574.723
PMID:3105708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1245787/
Abstract
摘要

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Overuse of monitoring of blood concentrations of antiepileptic drugs.抗癫痫药物血药浓度监测的过度使用。
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Guidelines for therapeutic monitoring on antiepileptic drugs. Commission on Antiepileptic Drugs, International League Against Epilepsy.抗癫痫药物治疗监测指南。国际抗癫痫联盟抗癫痫药物委员会。
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[Significance and limitations of blood level determinations of antiepileptic drugs].[抗癫痫药物血药浓度测定的意义与局限性]
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6
Should we measure free antiepileptic drug levels?我们应该检测游离抗癫痫药物水平吗？
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Therapeutic monitoring of antiepileptic drugs. I--Clinical aspects.抗癫痫药物的治疗监测。I——临床方面。
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Knowledge, attitude and practice in antiepileptic drug monitoring.抗癫痫药物监测中的知识、态度与实践
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[Study of the relation of cyclic 3,5-monophosphate and the concentration of antiepileptic agents in a group of resistant epileptics].[一组难治性癫痫患者中环状3,5 - 单磷酸与抗癫痫药物浓度关系的研究]
Neurologija. 1984;32(1-2):33-44.
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[Epilepsy and pregnancy. Seizure incidence and serum concentration of antiepileptic agents].[癫痫与妊娠。癫痫发作发生率及抗癫痫药物的血清浓度]
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Monitoring antiepileptic drugs: a level-headed approach.监测抗癫痫药物：一种冷静的方法。
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Therapeutic monitoring of antiepileptic drugs for epilepsy.癫痫抗癫痫药物的治疗监测
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Therapeutic drug monitoring--antiepileptic drugs.治疗药物监测——抗癫痫药物
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The management of epilepsy in the 1990s. Acquisitions, uncertainties and priorities for future research.20世纪90年代癫痫的管理。未来研究的进展、不确定性和优先事项。
Drugs. 1995 May;49(5):680-94. doi: 10.2165/00003495-199549050-00004.
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Disposition of anticonvulsants in childhood.儿童期抗惊厥药物的处置
Clin Pharmacokinet. 1989;17 Suppl 1:89-104. doi: 10.2165/00003088-198900171-00007.
8
Rapid anticonvulsant monitoring in an epilepsy clinic.癫痫诊所中的快速抗惊厥监测
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Medical assessment and treatment of chronic epilepsy.慢性癫痫的医学评估与治疗
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10
Use of plasma levels for antiepileptic drug monitoring in clinical practice. Gruppo Collaborativo per lo Studio dell'Epilessia.血浆水平在临床实践中用于抗癫痫药物监测。癫痫研究协作组。
Ital J Neurol Sci. 1992 Feb;13(1):59-65. doi: 10.1007/BF02222890.

本文引用的文献

1
Diurnal variations in steady-state plasma concentrations of valproic acid in epileptic patients.癫痫患者丙戊酸稳态血浆浓度的昼夜变化。
Clin Pharmacokinet. 1982 Nov-Dec;7(6):544-52. doi: 10.2165/00003088-198207060-00004.
2
"Therapeutic" serum concentration of phenytoin: the influence of seizure type.苯妥英钠的“治疗性”血清浓度：癫痫发作类型的影响
J Neurol Neurosurg Psychiatry. 1984 Mar;47(3):231-4. doi: 10.1136/jnnp.47.3.231.
3
Which drug for the adult epileptic patient: phenytoin or valproate?对于成年癫痫患者，使用哪种药物：苯妥英还是丙戊酸盐？
Br Med J (Clin Res Ed). 1985 Mar 16;290(6471):815-9. doi: 10.1136/bmj.290.6471.815.
4
Phenytoin kinetics during pregnancy and the puerperium.孕期及产褥期苯妥英钠的药代动力学
Br J Obstet Gynaecol. 1986 Oct;93(10):1030-7. doi: 10.1111/j.1471-0528.1986.tb07827.x.
5
One drug for epilepsy.一种治疗癫痫的药物。
Br Med J. 1978 Feb 25;1(6111):474-6. doi: 10.1136/bmj.1.6111.474.
6
The delayed effect of sodium valproate on the photoconvulsive response in man.
Epilepsia. 1979 Feb;20(1):61-8. doi: 10.1111/j.1528-1157.1979.tb04776.x.
7
Salivary phenytoin concentrations in epilepsy and in chronic renal failure.
Lancet. 1976 Aug 21;2(7982):384-6. doi: 10.1016/s0140-6736(76)92404-1.
8
Serum-phenytoin levels in management of epilepsy.癫痫治疗中血清苯妥英水平
Lancet. 1975 Aug 9;2(7928):247-8. doi: 10.1016/s0140-6736(75)90962-9.