Shah Swapnil D, Shah Amit, Ankad Bhalachandra, Mutalik Sharad
Department of Dermatology, Ashwini Rural Medical College, Hospital and Research Centre, Solapur, Maharashtra, India.
Shobhana Skin Cosmetic and Laser Clinic, Sangli, Maharashtra, India.
J Cutan Aesthet Surg. 2019 Jan-Mar;12(1):17-24. doi: 10.4103/JCAS.JCAS_138_18.
Halo nevus (HN) affects approximately 1% of the population. Presence of hypo- or depigmented lesion carries tremendous psychosocial disturbance in the mind-set of population in the Indian subcontinent. Hence, HN requires intervention by any modalities. Here authors attempted to evaluate the efficacy of monochromatic excimer light (MEL) in treating HN.
A total of 29 patients with HN were included in the study. A xenon chloride lamp emitting noncoherent, monochromatic 308-nm light that represents the natural evolution of the excimer laser was used. The initial dose was 100 mJ/cm, which was increased by 100 mJ/cm per session. All the patients were followed up for 6 months.
A total of 29 patients with 10 males and 19 females (male to female ratio of 1:1.9) completed the study. The age of onset of HN ranged from 5 to 47 years and the mean age of the patients was 23 years. HN was seen on the face, back, neck, chest, trunk, and extremities in 5 (17.2%), 6 (20.7%), 4 (13.7%), and 6 (20.7%) patients, respectively. Outstanding response was noticed in 14 patients (48.2%), whereas 6 (20.6%) patients showed excellent improvement. Only 2 (6.8%) patients showed no response after 10 consecutive sessions.
HN causes apprehension in the Indian population because of the social stigma associated with depigmented patches on the body. Mere observation and only counseling in the treatment protocol are not sufficient. MEL is a noninvasive procedure, which results in excellent repigmentation of HN without scarring.
晕痣（HN）影响约1%的人群。在印度次大陆，色素减退或脱失性皮损的出现给人们的心理带来极大的社会心理困扰。因此，HN需要通过任何方式进行干预。在此，作者试图评估单色准分子光（MEL）治疗HN的疗效。
本研究共纳入29例HN患者。使用了一种发射非相干单色308纳米光的氯化氙灯，它代表了准分子激光的自然演变。初始剂量为100 mJ/cm²，每次治疗增加100 mJ/cm²。所有患者随访6个月。
共有29例患者完成研究，其中男性10例，女性19例（男女比例为1:1.9）。HN的发病年龄在5至47岁之间，患者的平均年龄为23岁。HN分别出现在5例（17.2%）患者的面部、6例（20.7%）患者的背部、4例（13.7%）患者的颈部、6例（20.7%）患者的胸部、躯干和四肢。14例患者（48.2%）有显著反应，而6例（20.6%）患者有极佳改善。连续10次治疗后，只有2例（6.8%）患者无反应。
由于与身体上色素脱失斑相关的社会耻辱感，HN在印度人群中引起担忧。仅在治疗方案中进行观察和咨询是不够的。MEL是一种非侵入性手术，可使HN实现极佳的色素再沉着且不留疤痕。
