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Effect of chloroquine on insulin and glucose homeostasis in normal subjects and patients with non-insulin dependent diabetes mellitus.

作者信息

Rees Richard G, Smith Michael J

机构信息

Department of Rheumatology, Westminster Hospital, London SW1P 2AP

Royal Surrey County Hospital, Guildford, Surrey GU2 5XX

出版信息

Br Med J (Clin Res Ed). 1987 Apr 4;294(6576):900-1. doi: 10.1136/bmj.294.6576.900-c.

DOI:10.1136/bmj.294.6576.900-c
PMID:3105793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1245948/
Abstract
摘要

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1
Effect of chloroquine on insulin and glucose homeostasis in normal subjects and patients with non-insulin dependent diabetes mellitus.氯喹对正常人和非胰岛素依赖型糖尿病患者胰岛素及葡萄糖稳态的影响。
Br Med J (Clin Res Ed). 1987 Apr 4;294(6576):900-1. doi: 10.1136/bmj.294.6576.900-c.
2
Effect of chloroquine on insulin and glucose homoeostasis in normal subjects and patients with non-insulin-dependent diabetes mellitus.氯喹对正常人和非胰岛素依赖型糖尿病患者胰岛素及葡萄糖稳态的影响。
Br Med J (Clin Res Ed). 1987 Feb 21;294(6570):465-7. doi: 10.1136/bmj.294.6570.465.
3
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4
Five-compartment model of insulin kinetics and its use to investigate action of chloroquine in NIDDM.
Am J Physiol. 1993 Jul;265(1 Pt 1):E162-75. doi: 10.1152/ajpendo.1993.265.1.E162.
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Insulin internalization and degradation in adipocytes from normal and type II diabetic subjects.正常和II型糖尿病受试者脂肪细胞中胰岛素的内化与降解
J Clin Endocrinol Metab. 1986 Feb;62(2):268-74. doi: 10.1210/jcem-62-2-268.
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Zhonghua Yi Xue Za Zhi. 2007 May 15;87(18):1252-5.

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Infect Dis Ther. 2021 Mar;10(1):439-455. doi: 10.1007/s40121-021-00397-8. Epub 2021 Jan 23.
2
Antidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial.羟氯喹对胰岛素敏感性和β细胞功能的抗糖尿病作用：一项随机试验。
Diabetologia. 2015 Oct;58(10):2336-43. doi: 10.1007/s00125-015-3689-2. Epub 2015 Jul 22.
3
Hydroxychloroquine: a diabetic drug in disguise?羟氯喹：一种伪装成糖尿病药物的药物？
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.08.2008.0654. Epub 2009 Mar 2.

本文引用的文献

1
Insulin metabolism and degradation.胰岛素代谢与降解。
Endocr Rev. 1981 Spring;2(2):210-33. doi: 10.1210/edrv-2-2-210.
2
Insulin degradation by human skeletal muscle.
Biochim Biophys Acta. 1982 Nov 24;719(2):259-66. doi: 10.1016/0304-4165(82)90097-6.
3
Treatment of type I diabetic with subcutaneous insulin resistance by a totally implantable insulin infusion device ("Infusaid").使用完全植入式胰岛素输注装置（“Infusaid”）治疗伴有皮下胰岛素抵抗的I型糖尿病患者。
Diabetes Res. 1984 Jul;1(2):83-8.
4
In vivo chloroquine-induced inhibition of insulin degradation in a diabetic patient with severe insulin resistance.在一名患有严重胰岛素抵抗的糖尿病患者体内，氯喹诱导的胰岛素降解抑制作用。
Diabetes. 1984 Dec;33(12):1133-7. doi: 10.2337/diab.33.12.1133.
5
In search of the subcutaneous-insulin-resistance syndrome.寻找皮下胰岛素抵抗综合征。
N Engl J Med. 1986 Jul 17;315(3):147-53. doi: 10.1056/NEJM198607173150302.