Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX.
Department of Clinical and Health Psychology, College of Public Health and Health Professions.
Alzheimer Dis Assoc Disord. 2019 Jul-Sep;33(3):226-232. doi: 10.1097/WAD.0000000000000310.
The Montreal Cognitive Assessment (MoCA) is a popular screening tool for Mild Cognitive Impairment (MCI). The psychometric properties of the MoCA have not been widely examined in minority groups. We aimed to analyze the discriminate ability of subtests and items by race and ethnicity given gold-standard clinical diagnosis of cognitive status.
We analyzed data from the National Alzheimer Coordinating Center Uniform Data Set March 2018 data freeze. Stepwise regression was used to determine which subtests predicted cognitive status (normal cognition, MCI, or dementia), by race/ethnicity. Item discrimination and difficulty was calculated by race/ethnicity and cognitive status.
In our sample (n=3895), with an average age of 69.7, 80.7% were non-Hispanic white, 15.0% were non-Hispanic black, and 4.2% were Hispanic. Among non-Hispanic whites all subtests, education, and age predicted clinician diagnosis, while visuospatial/executive, attention, language, delayed recall, and orientation subtests were predictive among non-Hispanic blacks and visuospatial/executive, delayed recall, and orientation subtests and education were predictive among Hispanics. Item discrimination and difficulty varied by race/ethnicity and cognitive status.
By understanding the psychometric properties of MoCA subtests, we can focus on subtests that have higher discrimination and more diagnostic utility. Subtests should be further evaluated for use in screening of minority individuals.
蒙特利尔认知评估(MoCA)是一种常用于轻度认知障碍(MCI)的筛查工具。MoCA 的心理测量特性在少数群体中尚未得到广泛研究。我们旨在根据认知状态的金标准临床诊断,分析种族和民族群体中各亚测试和项目的区分能力。
我们分析了 2018 年 3 月国家阿尔茨海默病协调中心统一数据集冻结的数据。逐步回归用于根据种族/民族确定哪些亚测试预测认知状态(正常认知、MCI 或痴呆)。按种族/民族和认知状态计算项目的区分度和难度。
在我们的样本(n=3895)中,平均年龄为 69.7 岁,80.7%为非西班牙裔白人,15.0%为非西班牙裔黑人,4.2%为西班牙裔。在非西班牙裔白人群体中,所有亚测试、教育和年龄均预测了临床医生的诊断,而在非西班牙裔黑人和西班牙裔中,视空间/执行、注意力、语言、延迟回忆和定向亚测试具有预测性,而视空间/执行、延迟回忆和定向亚测试和教育具有预测性。项目的区分度和难度因种族/民族和认知状态而异。
通过了解 MoCA 亚测试的心理测量特性,我们可以专注于具有更高区分度和更多诊断效用的亚测试。应进一步评估亚测试用于筛查少数群体个体。