影响房水中抗坏血酸氧化的因素。

Factors affecting ascorbate oxidation in aqueous humor.

作者信息

Fong D, Etzel K, Lee P F, Lin T Y, Lam K W

出版信息

Curr Eye Res. 1987 Feb;6(2):357-61. doi: 10.3109/02713688709025188.

Abstract

Aqueous humor from human glaucomatous eyes was divided into two groups. Group I aqueous humor contains a negligible amount of ascorbate, while group II contains ascorbate. Group I aqueous humor stimulates ascorbate oxidation. This oxidative effect is inhibited by the addition of EDTA, indicating the presence of metallic ions. The amount of copper determined by atomic spectrophotometry in these samples was 1.54 micrograms/ml. On the contrary, group II aqueous humor protects against ascorbate oxidation. The small amount of albumin present in these samples accounts for part of this protective effect.

摘要

来自人类青光眼患者眼睛的房水被分为两组。第一组房水中抗坏血酸盐含量可忽略不计，而第二组含有抗坏血酸盐。第一组房水会刺激抗坏血酸盐氧化。这种氧化作用会被添加的乙二胺四乙酸（EDTA）抑制，这表明存在金属离子。通过原子分光光度法测定这些样本中的铜含量为1.54微克/毫升。相反，第二组房水可防止抗坏血酸盐氧化。这些样本中存在的少量白蛋白是这种保护作用的部分原因。