Ogawa Fumihiro, Sakai Takuma, Takahashi Ko, Kato Makoto, Yamaguchi Keishi, Okazaki Sayo, Abe Takeru, Iwashita Masayuki, Takeuchi Ichiro
Department of Emergency Medicine, Yokohama City University School of Medicine, Yokohama, 232-0024, Japan.
Advanced Critical Care and Emergency Center, Yokohama City University Medical Center, Yokohama, 232-0024, Japan.
J Cardiothorac Surg. 2019 May 6;14(1):88. doi: 10.1186/s13019-019-0908-9.
The use of veno-venous extracorporeal membrane oxygenation (VV-ECMO) in trauma patients has been controversial, but VV-ECMO plays a crucial role when the lungs are extensively damaged and when conventional management has failed. VV-ECMO provides adequate tissue oxygenation and an opportunity for lung recovery. However, VV-ECMO remains contraindicated in patients with a risk of bleeding because of systemic anticoagulation during the treatment. The most important point is controlling the bleeding from severe trauma.
A 32-year-old male experienced blunt trauma due to a traffic accident. He presented with bilateral hemopneumothorax and bilateral flail chest. We performed emergency thoracotomy for active bleeding and established circulatory stability. After surgery, the oxygenation deteriorated under mechanical ventilation, so we decided to establish VV-ECMO. However, bleeding from the bilateral lung contusions increased after VV-ECMO was established, and the patient was switched to heparin-free ECMO. After conversion, we could control the bronchial bleeding, especially the lung hematomas, and the oxygenation recovered. The patient was discharged without significant complications. VV-ECMO and mechanical ventilation were stopped on days 10 and 11, respectively. He was discharged from the ICU on day 15.
When we consider the use of ECMO for patients with uncontrollable, severe bleeding caused by blunt trauma, it may be necessary to use a higher flow setting for heparin-free ECMO than typically used for patients without trauma to prevent thrombosis.
在创伤患者中使用静脉-静脉体外膜肺氧合(VV-ECMO)一直存在争议,但当肺部受到广泛损伤且传统治疗失败时,VV-ECMO发挥着关键作用。VV-ECMO可提供充足的组织氧合,并为肺恢复创造机会。然而,由于治疗期间需要全身抗凝,VV-ECMO在有出血风险的患者中仍属禁忌。最重要的是控制严重创伤引起的出血。
一名32岁男性因交通事故遭受钝性创伤。他出现双侧血气胸和双侧连枷胸。我们对活动性出血进行了紧急开胸手术,并建立了循环稳定。术后,机械通气下氧合恶化,因此我们决定建立VV-ECMO。然而,建立VV-ECMO后双侧肺挫伤出血增加,患者改用无肝素ECMO。转换后,我们能够控制支气管出血,尤其是肺血肿,氧合恢复。患者出院时无明显并发症。分别在第10天和第11天停止使用VV-ECMO和机械通气。他于第15天从重症监护病房出院。
当我们考虑对因钝性创伤导致无法控制的严重出血患者使用ECMO时,可能有必要对无肝素ECMO使用比通常用于非创伤患者更高的流量设置以预防血栓形成。