Department of Radiation Oncology, University of Michigan, Ann Arbor, MI.
Department of Radiation Oncology, Hunter Holmes McGuire VA Medical Center, Richmond, VA.
Urol Oncol. 2019 Sep;37(9):599-610. doi: 10.1016/j.urolonc.2019.04.009. Epub 2019 May 3.
Interstitial brachytherapy is one of several curative therapeutic options for the treatment of localized prostate cancer. In this review, we summarize all available randomized data to support the optimal use of prostate brachytherapy. Evidence from completed randomized controlled trials is the focus of this review with a presentation also of important ongoing trials. Gaps in knowledge are identified where future investigation may be fruitful with intent to inspire well-designed prospective studies with standardized treatment that focuses on improving oncological outcomes, reducing morbidity, or maintaining quality of life.
间质内近距离放射治疗是局部前列腺癌治疗的几种有治愈可能的治疗选择之一。在这篇综述中，我们总结了所有可用的随机数据，以支持前列腺近距离放射治疗的最佳应用。本综述的重点是已完成的随机对照试验的证据，并介绍了一些重要的正在进行的试验。本文还确定了知识空白领域，未来的研究可能会在此取得成果，并旨在激励进行精心设计的前瞻性研究，标准化治疗，重点是改善肿瘤学结果、降低发病率或维持生活质量。
