Mallick Bipadabhanjan, Malik Sarthak, Gupta Pankaj, Gorsi Ujjwal, Kochhar Suman, Gupta Vikas, Yadav Thakur Deen, Dhaka Narendra, Sinha Saroj K, Kochhar Rakesh
Department of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.
Department of Radiodiagnosis Postgraduate Institute of Medical Education and Research Chandigarh India.
JGH Open. 2018 Dec 26;3(2):126-132. doi: 10.1002/jgh3.12116. eCollection 2019 Apr.
To evaluate the clinical profile and outcome of arterial pseudoaneurysms (PSA) associated with acute and chronic pancreatitis (CP).
Records of all patients of pancreatitis from 2010 to 2016 were analyzed retrospectively for the development PSAs; clinical profile and outcome parameters were compared between PSAs associated with acute and CP.
Of the 980 patients, 46 (all males, age 39.70 ± 11.78 years) developed PSAs, including 19 of 600 of acute pancreatitis (AP) and 27 of 380 of CP. The most common clinical presentation was bleeding (37, 80.4%). The majority of patients was managed nonsurgically, with endovascular embolization in 31 (67.4%) and percutaneous thrombin injection in 9 (19.6%) patients. Pseudoaneurysms in patients with AP were associated more often with fluid collections (94.7% vs. 55.6%, = 0.004) with more requirement of surgery compared to patients with CP (15.8% vs. 3.7%, = 0.033). The pattern of arteries involved with PSAs and outcome was similar in AP and CP patients.
Arterial PSAs were more commonly associated with CP compared to AP with similar presentations. Associated fluid collections and requirement of surgical intervention were higher in PSAs in patients with AP compared to patients with CP.
评估与急性和慢性胰腺炎(CP)相关的动脉假性动脉瘤(PSA)的临床特征及预后。
回顾性分析2010年至2016年所有胰腺炎患者的病历,以确定PSA的发生情况;比较与急性胰腺炎和CP相关的PSA的临床特征及预后参数。
在980例患者中,46例(均为男性,年龄39.70±11.78岁)发生PSA,其中急性胰腺炎(AP)600例中有19例,CP 380例中有27例。最常见的临床表现是出血(37例,80.4%)。大多数患者采用非手术治疗,31例(67.4%)接受血管内栓塞,9例(19.6%)接受经皮凝血酶注射。与CP患者相比,AP患者的假性动脉瘤更常与液体积聚相关(94.7%对55.6%,P = 0.004),且手术需求更高(15.8%对3.7%,P = 0.033)。AP和CP患者中与PSA相关的动脉模式及预后相似。
与AP相比,CP更常伴有动脉PSA,二者临床表现相似。与CP患者相比,AP患者的PSA相关液体积聚及手术干预需求更高。