Programa de Genómica Funcional de Procariotes, Centro de Ciencias Genómicas-Universidad Nacional Autónoma de México, Cuernavaca, Morelos, C.P. 62210, Mexico.
FEMS Microbiol Lett. 2019 Apr 1;366(7). doi: 10.1093/femsle/fnz084.
Polyamines are ubiquitous molecules containing two or more amino groups that fulfill varied and often essential physiological and regulatory roles in all organisms. In the symbiotic nitrogen-fixing bacteria known as rhizobia, putrescine and homospermidine are invariably produced while spermidine and norspermidine synthesis appears to be restricted to the alfalfa microsymbiont Sinorhizobium meliloti. Studies with rhizobial mutants deficient in the synthesis of one or more polyamines have shown that these compounds are important for growth, stress resistance, motility, exopolysaccharide production and biofilm formation. In this review, we describe these studies and examine how polyamines are synthesized and regulated in rhizobia.
多胺是一类普遍存在的分子，含有两个或多个氨基，在所有生物中发挥着多样化且通常是必需的生理和调节作用。在共生固氮细菌根瘤菌中，腐胺和高亚精胺总是被产生，而精胺和亚精胺的合成似乎仅限于紫花苜蓿共生菌根瘤菌属。对多胺合成缺陷的根瘤菌突变体的研究表明，这些化合物对生长、抗应激、运动性、胞外多糖产生和生物膜形成很重要。在这篇综述中，我们描述了这些研究，并探讨了多胺在根瘤菌中的合成和调控方式。
