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[假单胞菌免疫球蛋白在跨学科外科重症监护病房人工呼吸患者中的应用]

[Use of Pseudomonas immunoglobulin in artificially respirated patients at an interdisciplinary surgical intensive care unit].

作者信息

Class I, Junginger W, Klöss T

出版信息

Infection. 1987 Jan-Feb;15(1):76-9. doi: 10.1007/BF01646128.

Abstract

The clinical efficacy and safety of a new pseudomonas hyperimmune globulin for intravenous administration were examined in 30 patients in a prospective randomized study. Although the statistical evaluation of the measurable parameters did not show relevant differences between the therapy group (n = 15) and the controls (n = 15), the clinical course of the disease was markedly better in patients treated with hyperimmune globulin. In the control group, three patients died from Pseudomonas aeruginosa infections, but none in the therapy group. The preparation was very well tolerated.

摘要

在一项前瞻性随机研究中,对30例患者检验了一种新的静脉注射用假单胞菌超免疫球蛋白的临床疗效和安全性。尽管对可测量参数的统计评估未显示治疗组(n = 15)和对照组(n = 15)之间存在显著差异,但接受超免疫球蛋白治疗的患者的疾病临床进程明显更好。在对照组中,有3例患者死于铜绿假单胞菌感染,而治疗组中无死亡病例。该制剂耐受性良好。

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