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90岁以上慢性硬膜下血肿患者的临床治疗结果。

Clinical Outcome of Patients Over 90 Years of Age Treated for Chronic Subdural Hematoma.

作者信息

Dobran Mauro, Marini Alessandra, Nasi Davide, Liverotti Valentina, Benigni Roberta, Costanza Martina Della, Mancini Fabrizio, Scerrati Massimo

机构信息

Department of Neurosurgery, Umberto I General Hospital, Università Politecnica delle Marche, Ancona, Italy.

出版信息

J Korean Neurosurg Soc. 2022 Jan;65(1):123-129. doi: 10.3340/jkns.2018.0011. Epub 2019 May 7.

Abstract

OBJECTIVE

Chronic subdural hematoma (CSDH) is one of the most common pathology in daily neurosurgical practice and incidence increases with age. The aim of this study was to evaluate the prognostic factors and surgical outcome of CSDH in patients aging over 90 years compared with a control group of patients aging under 90 years.

METHODS

This study reviewed 25 patients with CSDH aged over 90 years of age treated in our department. This group was compared with a younger group of 25 patients aged below their eighties. At admission past medical history was recorded concerning comorbidities (hypertension, dementia, ictus cerebri, diabetes, and heart failure or attack). History of alcohol abuse, anticoagulant and antiplatelet therapy, head trauma and seizures were analyzed. Standard neurological examination and Markwalder score at admission, 48 hours after surgery and 1-6 months follow-up, radiologic data including location and CSDH maximum thickness were also evaluated.

RESULTS

Their mean age was 92.8 years and the median was 92.4 years (range, 90-100 years). In older group, the Markwalder evaluation at one month documented the complete recovery of 24 patients out of 25 without statistical difference with the younger group. This data was confirmed at 6-month follow-up. One patient died from cardiovascular failure 20 days after surgery. The presence of comorbidities, risk factors (antiplatelet therapy, anticoagulant therapy, history of alcohol abuse, and head trauma), preoperative symptoms, mono or bilateral CSDH, maximum thickness of hematoma, surgical time and recurrence were similar and statistically not significant in both groups.

CONCLUSION

In this study, we demonstrate that surgery for very old patients above 90 years of age affected by CSDH is safe and allows complete recovery. Comparing two groups of patients above and under 90 years old we found that complication rate and recovery were similar in both groups.

摘要

目的

慢性硬膜下血肿(CSDH)是日常神经外科实践中最常见的病症之一,其发病率随年龄增长而增加。本研究的目的是评估90岁以上CSDH患者的预后因素和手术结果,并与90岁以下的对照组患者进行比较。

方法

本研究回顾了在我科接受治疗的25例90岁以上的CSDH患者。将该组与25例80岁以下的年轻患者组进行比较。入院时记录既往病史,包括合并症(高血压、痴呆、脑卒中、糖尿病以及心力衰竭或发作)。分析酗酒史、抗凝和抗血小板治疗史、头部外伤史和癫痫发作史。还评估了入院时、手术后48小时以及1 - 6个月随访时的标准神经系统检查和Markwalder评分,以及包括血肿位置和最大厚度在内的放射学数据。

结果

他们的平均年龄为92.8岁,中位数为92.4岁(范围90 - 100岁)。在老年组中,1个月时的Markwalder评估显示25例患者中有24例完全康复,与年轻组无统计学差异。6个月随访时证实了该数据。1例患者术后20天死于心血管衰竭。两组在合并症、危险因素(抗血小板治疗、抗凝治疗、酗酒史和头部外伤)、术前症状、单或双侧CSDH、血肿最大厚度、手术时间和复发情况方面相似,且无统计学差异。

结论

在本研究中,我们证明,对于90岁以上受CSDH影响的高龄患者进行手术是安全的,且能实现完全康复。比较90岁以上和90岁以下的两组患者,我们发现两组的并发症发生率和恢复情况相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f628/8752881/947d6ae5cf16/jkns-2018-0011f1.jpg

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