Lauweryns J M, Van Ranst L
J Histochem Cytochem. 1987 Jun;35(6):687-91. doi: 10.1177/35.6.3106468.
Anti-Leu 7 is a monoclonal antibody recognizing a surface antigen on human natural killer cells. By applying the indirect immunoperoxidase method, we demonstrated Leu-7 immunoreactivity in the cytoplasm of neuroepithelial bodies (NEB) and neuroendocrine cells (NEC) of human, monkey, and pig respiratory mucosa. In addition, the anti-Leu-7 monoclonal antibody stained the myelin sheaths of nerve fibers in all tissues investigated. Our findings support the hypothesis that shared antigens exist between the nervous, endocrine, and immune systems.
抗Leu 7是一种识别人类自然杀伤细胞表面抗原的单克隆抗体。通过应用间接免疫过氧化物酶法，我们在人、猴和猪呼吸道黏膜的神经上皮小体（NEB）和神经内分泌细胞（NEC）的细胞质中证实了Leu-7免疫反应性。此外，抗Leu-7单克隆抗体对所有研究组织中的神经纤维髓鞘进行了染色。我们的研究结果支持了神经、内分泌和免疫系统之间存在共同抗原这一假说。
