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第一激素:肾上腺素。

The First Hormone: Adrenaline.

机构信息

Peking University, Division of Sciences, 5 Yiheyuan Road, Beijing, China.

出版信息

Trends Endocrinol Metab. 2019 Jun;30(6):331-334. doi: 10.1016/j.tem.2019.03.005. Epub 2019 May 4.

Abstract

It is not often that three misconceptions are associated with one molecule for more than a century. This is the case with adrenaline. The aim here is to clarify that adrenaline was the first hormone, with the discovery of its activity and chemical purification being prior to secretin. Adrenaline is the correct name given by Jōkichi Takamine, epinephrine being its inactive benzoyl derivative.

摘要

一个分子在一个多世纪内与三个误解相关联的情况并不常见。这就是肾上腺素的情况。这里的目的是澄清肾上腺素是第一种激素,其活性的发现和化学纯化先于促胰液素。肾上腺素是 Jōkichi Takamine 赋予的正确名称,而肾上腺素是其无活性的苯甲酰衍生物。

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