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不同内脏、肾、肾上腺及脑静脉中促甲状腺激素释放激素的血浆水平。

Plasma levels of thyrotropin-releasing-hormone in various splanchnic, renal, suprarenal, and cerebral veins.

作者信息

Vardarl I, Wdowinski J M, Hoevels J, Schmidt R, Schwedes U, Georgi M, Usadel K H

出版信息

Klin Wochenschr. 1987 Feb 2;65(3):134-7. doi: 10.1007/BF01728606.

DOI:10.1007/BF01728606
PMID:3106709
Abstract

Endogenous TRH levels were determined in plasma obtained selectively via percutaneous transhepatic and femoral catheterization. TRH was measured using a very sensitive RIA method. In the pancreatic veins, internal jugular vein, left testicular vein, and other described veins, normal peripheral levels were found. An involvement of the TRH degrading enzyme (TDE) or a rapid intravasal dilution leading to normal peripheral TRH levels in the veins leaving the brain or pancreas, respectively, is discussed.

摘要

通过经皮肝穿刺和股静脉插管选择性获取血浆,测定内源性促甲状腺激素释放激素(TRH)水平。采用非常灵敏的放射免疫分析(RIA)方法测量TRH。在胰腺静脉、颈内静脉、左侧睾丸静脉以及其他所述静脉中,均发现外周血TRH水平正常。文中讨论了TRH降解酶(TDE)的作用,或分别导致离开脑或胰腺的静脉中TRH外周血水平正常的快速血管内稀释作用。

相似文献

1
Plasma levels of thyrotropin-releasing-hormone in various splanchnic, renal, suprarenal, and cerebral veins.不同内脏、肾、肾上腺及脑静脉中促甲状腺激素释放激素的血浆水平。
Klin Wochenschr. 1987 Feb 2;65(3):134-7. doi: 10.1007/BF01728606.
2
Pancreatic vein catheterization with gastrin assay in normal patients and in patients with the Zollinger-Ellison syndrome.正常患者及佐林格-埃利森综合征患者的胰腺静脉插管及胃泌素测定
Am J Surg. 1977 Nov;134(5):558-63. doi: 10.1016/0002-9610(77)90433-0.
3
Thyroid hormones modulate thyrotropin-releasing hormone biosynthesis in tissues outside the hypothalamic-pituitary axis of male rats.甲状腺激素调节雄性大鼠下丘脑 - 垂体轴以外组织中促甲状腺激素释放激素的生物合成。
Endocrinology. 1989 Jul;125(1):524-31. doi: 10.1210/endo-125-1-524.
4
Thyrotropin-releasing hormone in the systemic circulation of the neonatal rat is derived from the pancreas and other extraneural tissues.新生大鼠体循环中的促甲状腺激素释放激素源自胰腺和其他神经外组织。
J Clin Invest. 1981 Mar;67(3):800-8. doi: 10.1172/JCI110097.
5
Plasma thyrotropin-releasing hormone, prolactin, thyrotropin, and thyroxine concentrations following the intravenous or oral administration of thyrotropin-releasing hormone.静脉注射或口服促甲状腺激素释放激素后血浆促甲状腺激素释放激素、催乳素、促甲状腺激素和甲状腺素的浓度
Am J Obstet Gynecol. 1979 Nov 15;135(6):737-42. doi: 10.1016/0002-9378(79)90384-3.
6
Paradoxical response of plasma beta-endorphin to combined administration of TRH and GnRH in adrenal disorders.血浆β-内啡肽对促甲状腺激素释放激素和促性腺激素释放激素联合给药在肾上腺疾病中的矛盾反应。
Exp Clin Endocrinol. 1989 Sep;94(1-2):157-62. doi: 10.1055/s-0029-1210892.
7
Thyrotropin-releasing hormone cannot be detected in plasma from normal subjects.正常受试者的血浆中无法检测到促甲状腺激素释放激素。
J Clin Endocrinol Metab. 1986 Aug;63(2):516-9. doi: 10.1210/jcem-63-2-516.
8
[Hormone levels of the blood of the adrenal veins and inferior vena cava in patients with adrenal and kidney diseases].[肾上腺及肾脏疾病患者肾上腺静脉与下腔静脉血液中的激素水平]
Med Radiol (Mosk). 1985 Jul;30(7):27-31.
9
Thyrotropin-releasing hormone in ovine fetus: ontogeny and effect of thyroid hormone.绵羊胎儿体内的促甲状腺激素释放激素:个体发育及甲状腺激素的影响
Am J Physiol. 1991 Jan;260(1 Pt 1):E53-8. doi: 10.1152/ajpendo.1991.260.1.E53.
10
Inhibition of degradation and measurement of immunoreactive thyrotropin-releasing hormone in rat blood and plasma.大鼠血液和血浆中促甲状腺激素释放激素降解的抑制及免疫反应性测定
Endocrinology. 1976 Feb;98(2):269-77. doi: 10.1210/endo-98-2-269.

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Prospective evaluation of aminopeptidase activities in plasma and peripheral organs of streptozotocin-induced diabetic rats.链脲佐菌素诱导的糖尿病大鼠血浆和外周器官中氨肽酶活性的前瞻性评估。
J Endocrinol Invest. 2008 Jun;31(6):492-8. doi: 10.1007/BF03346396.

本文引用的文献

1
Thyrotropin-releasing hormone.促甲状腺激素释放激素
N Engl J Med. 1982 Jan 21;306(3):145-55. doi: 10.1056/NEJM198201213060305.
2
A prolactin inhibitory factor with immunocharacteristics similar to thyrotropin releasing factor (TRH) is present in rat pituitary tumors (GH3 and W5), testicular tissue and a plant material, alfalfa.
Biochem Biophys Res Commun. 1980 Sep 16;96(1):47-53. doi: 10.1016/0006-291x(80)91179-1.
3
[Molecular structure of the hypothalamic hypophysiotropic TRF factor of ovine origin: mass spectrometry demonstration of the PCA-His-Pro-NH2 sequence].[绵羊下丘脑促垂体TRF因子的分子结构:主链氨基端为PCA-组氨酸-脯氨酸-NH₂序列的质谱鉴定]
C R Acad Hebd Seances Acad Sci D. 1969 Nov 12;269(19):1870-3.
4
Regulation of degradation of thyrotropin releasing hormone by thyroid hormones.甲状腺激素对促甲状腺激素释放激素降解的调节。
Nature. 1976 Feb 19;259(5544):591-3. doi: 10.1038/259591a0.
5
Percutaneous transhepatic portography.经皮肝门静脉造影术
Acta Radiol Diagn (Stockh). 1978;19(4):643-55. doi: 10.1177/028418517801900410.
6
Thyrotropin-releasing hormone in the gastrointestinal tract.胃肠道中的促甲状腺激素释放激素。
Biochem Biophys Res Commun. 1977 Nov 7;79(1):314-8. doi: 10.1016/0006-291x(77)90097-3.
7
Thyrotropin-releasing factor: distribution in neural and gastrointestinal tissues.促甲状腺激素释放因子:在神经组织和胃肠道组织中的分布。
Acta Physiol Scand. 1978 Oct;104(2):175-9. doi: 10.1111/j.1748-1716.1978.tb06264.x.
8
High concentration of thyrotropin-releasing hormone in pancreatic islets.胰岛中促甲状腺激素释放激素的高浓度。
Proc Natl Acad Sci U S A. 1978 Sep;75(9):4265-7. doi: 10.1073/pnas.75.9.4265.