Slusarczyk J, Hess G, Hansson B G, Meyer Zum Büschenfelde K H
Liver. 1986 Dec;6(6):337-40. doi: 10.1111/j.1600-0676.1986.tb00301.x.
The sera of 15 individuals with transfusion-associated acute or chronic non A, non B hepatitis, which lacked hepatitis B virus markers, were tested for hepatitis B virus DNA by dot blot hybridization test. Three sera of two patients positive in this test, however, also gave positive results when the labeled plasmid was used as probe instead of labeled HBV-DNA, indicating false positive results in the initial test. In conclusion, the data indicated that sera of patients with confirmed non A, non B hepatitis do not contain DNA-sequences in the serum hybridizing with HBV-DNA.
对15例输血相关的急性或慢性非甲非乙型肝炎患者(其血清缺乏乙肝病毒标志物)的血清进行斑点杂交试验,以检测乙肝病毒DNA。然而,在该试验中呈阳性的两名患者的三份血清,当使用标记质粒而非标记乙肝病毒DNA作为探针时,也得出了阳性结果,这表明初始试验结果为假阳性。总之,数据表明,确诊为非甲非乙型肝炎患者的血清中不含有能与乙肝病毒DNA杂交的血清DNA序列。